Local and whole-body SAR in UHF body imaging: Implications for SAR matrix compression.

PURPOSE: Transmit arrays for body imaging have characteristics of both volume and local transmit coils. This study evaluates two specific absorption rate (SAR) aspects, local and whole-body SAR, of arrays for body imaging at 7 T and also for a 3 T birdcage. METHODS: Simulations were performed for six antenna arrays at 7 T and one 3 T birdcage. Local SAR matrices and the whole-body SAR matrix were computed and evaluated with random shims. A set of reduced local SAR matrices was determined by removing all matrices dominated by the whole-body SAR matrix. RESULTS: The results indicate that all RF transmit coils for body imaging in this study are constrained by the local SAR limit. The ratio between local and whole-body SAR is nevertheless smaller for arrays with large FOV, as these arrays also expose a larger part of the human body. By using the whole-body SAR matrix, the number of local SAR matrices can be reduced (e.g., 33.3% matrices remained for an 8-channel local array and 89.7% for a 30-channel remote array; 12.1% for the 3 T birdcage). CONCLUSION: For transmit antenna arrays used for body imaging at 7 T as well as for the 3 T birdcage, all evaluated cases show that the local SAR limit was reached before reaching the whole-body SAR limit. Nevertheless, the whole-body SAR matrix can be used to reduce the number of local SAR matrices, which is important to reduce memory and computing time for a virtual observation points (VOP) compression. This step can be included as a pre-compression prior to a VOP compression.

Local SAR management strategies to use two-channel RF shimming for fetal MRI at 3 T.

PURPOSE: This study evaluates the imaging performance of two-channel RF-shimming for fetal MRI at 3 T using four different local specific absorption rate (SAR) management strategies. METHODS: Due to the ambiguity of safe local SAR levels for fetal MRI, local SAR limits for RF shimming were determined based on either each individual's own SAR levels in standard imaging mode (CP mode) or the maximum SAR level observed across seven pregnant body models in CP mode. Local SAR was constrained either indirectly by further constraining the whole-body SAR (wbSAR) or directly by using subject-specific local SAR models. Each strategy was evaluated by the improvement of the transmit field efficiency (average |B1 + |) and nonuniformity (|B1 + | variation) inside the fetus compared with CP mode for the same wbSAR. RESULTS: Constraining wbSAR when using RF shimming decreases B1 + efficiency inside the fetus compared with CP mode (by 12%-30% on average), making it inefficient for SAR management. Using subject-specific models with SAR limits based on each individual's own CP mode SAR value, B1 + efficiency and nonuniformity are improved on average by 6% and 13% across seven pregnant models. In contrast, using SAR limits based on maximum CP mode SAR values across seven models, B1 + efficiency and nonuniformity are improved by 13% and 25%, compared with the best achievable improvement without SAR constraints: 15% and 26%. CONCLUSION: Two-channel RF-shimming can safely and significantly improve the transmit field inside the fetus when subject-specific models are used with local SAR limits based on maximum CP mode SAR levels in the pregnant population.

Body-loop related MRI radiofrequency-induced heating hazards: Observations, characterizations, and recommendations.

PURPOSE: To assess RF-induced heating hazards in 1.5T MR systems caused by body-loop postures. METHODS: Twelve advanced high-resolution anatomically correct human body models with different body-loop postures are created based on poseable human adult male models. Numerical simulations are performed to assess the radiofrequency (RF)-induced heating of these 12 models at 11 landmarks. A customized phantom is developed to validate the numerical simulations and quantitatively analyze factors affecting the RF-induced heating, eg, the contact area, the loop size, and the loading position. The RF-induced heating inside three differently posed phantoms is measured. RESULTS: The RF-induced heating from the body-loop postures can be up to 11 times higher than that from the original posture. The RF-induced heating increases with increasing body-loop size and decreasing contact area. The magnetic flux increases when the body-loop center and the RF coil isocenter are close to each other, leading to increased RF-induced heating. An air gap created in the body loop or generating a polarized magnetic field parallel to the body loop can reduce the heating by a factor of three at least. Experimental measurements are provided, validating the correctness of the numerical results. CONCLUSION: Safe patient posture during MR examinations is recommended with the use of insulation materials to prevent loop formation and consequently avoiding high RF-induced heating. If body loops cannot be avoided, the body loop should be placed outside the RF transmitting coil. In addition, linear polarization with magnetic fields parallel to the body loop can be used to circumvent high RF-induced heating.

Post-processing algorithms for specific absorption rate compression.

PURPOSE: Compression of local specific absorption rate (SAR) matrices is essential for enabling SAR monitoring and efficient pulse calculation in parallel transmission. Improvements in compression result in lower error margin and/or lower number of virtual observation points (VOPs). The purpose of this work is to introduce two algorithms for post-processing of already compressed VOP sets. One calculates individual overestimation matrices for the VOPs to reduce overestimation, the other identifies redundant VOPs. METHODS: The first algorithm was evaluated for VOP sets calculated for three different transmit arrays with either 8 or 16 channels. For each array, two different overestimation matrices were used to generate the VOP sets. Each post-processed VOP set was evaluated using one million random excitation vectors and the results compared to the VOP set before post-processing. The second algorithm was evaluated by utilizing the same random excitation vectors and comparing the results after removal of the redundant VOPs with the results before removal to verify that these were identical. RESULTS: The first algorithm reduced the mean overestimation by up to four fifths compared to the original set, while keeping the number of VOPs constant. The second algorithm decreased the number of VOPs generated by a compression with Eichfelder and Gebhardt's algorithm by more than 40% in 40% of the investigated cases and by more than 20% in 73% of the investigated cases. CONCLUSION: Two post-processing algorithms are presented that enhance previously compressed VOP sets by improving the accuracy per number of VOPs.

Local SAR compression algorithm with improved compression, speed, and flexibility.

PURPOSE: Local specific absorption rate (SAR) compression algorithms are essential for enabling online SAR monitoring in parallel transmission. A better compression resulting in a lower number of virtual observation points improves speed of SAR calculation for online supervision and pulse design. METHOD: An iterative expansion of an existing algorithm presented by Lee et al is proposed in this work. The original algorithm is used within a loop, making use of the virtual observation points from the previous iteration as the starting subvolume, while decreasing the overestimation with each iteration. This algorithm is evaluated on the SAR matrices of three different simulated arrays. RESULT: The number of virtual observation points is approximately halved with the new algorithm, while at the same time the compression time is reduced with speed-up factors of up to 2.5. CONCLUSION: The new algorithm improves the original algorithm in terms of compression rate and speed.

Real-time assessment of potential peak local specific absorption rate value without phase monitoring: Trigonometric maximization method for worst-case local specific absorption rate determination.

PURPOSE: Multi-transmit MRI systems are typically equipped with dedicated hardware to sample the reflected/lost power in the transmit channels. After extensive calibration, the amplitude and phase of the signal at the feed of each array element can be accurately determined. However, determining the phase is more difficult and monitoring errors can lead to a hazardous peak local specific absorption rate (pSAR10g ) underestimation. For this purpose, methods were published for online maximum potential pSAR10g estimation without relying on phase monitoring, but these methods produce considerable overestimation. We present a trigonometric maximization method to determine the actual worst-case pSAR10g without any overestimation. THEORY AND METHOD: The proposed method takes advantage of the sinusoidal relation between the SAR10g in each voxel and the phases of input signals, to return the maximum achievable SAR10g in a few iterations. The method is applied to determine the worst-case pSAR10g for three multi-transmit array configurations at 7T: (1) body array with eight fractionated dipoles; (2) head array with eight fractionated dipoles; (3) head array with eight rectangular loops. The obtained worst-case pSAR10g values are compared with the pSAR10g values determined with a commonly used method and with a more efficient method based on reference-phases. RESULTS: For each voxel, the maximum achievable SAR10g is determined in less than 0.1 ms. Compared to the reference-phases-based method, the proposed method reduces the mean overestimation of the actual pSAR10g up to 52%, while never underestimating the true pSAR10g . CONCLUSION: The proposed method can widely improve the performance of parallel transmission MRI systems without phase monitoring.

Local SAR compression with overestimation control to reduce maximum relative SAR overestimation and improve multi-channel RF array performance.

OBJECTIVE: In local SAR compression algorithms, the overestimation is generally not linearly dependent on actual local SAR. This can lead to large relative overestimation at low actual SAR values, unnecessarily constraining transmit array performance. METHOD: Two strategies are proposed to reduce maximum relative overestimation for a given number of VOPs. The first strategy uses an overestimation matrix that roughly approximates actual local SAR; the second strategy uses a small set of pre-calculated VOPs as the overestimation term for the compression. RESULT: Comparison with a previous method shows that for a given maximum relative overestimation the number of VOPs can be reduced by around 20% at the cost of a higher absolute overestimation at high actual local SAR values. CONCLUSION: The proposed strategies outperform a previously published strategy and can improve the SAR compression where maximum relative overestimation constrains the performance of parallel transmission.

Conditional safety margins for less conservative peak local SAR assessment: A probabilistic approach.

PURPOSE: The introduction of a linear safety factor to address peak local specific absorption rate (pSAR10g ) uncertainties (eg, intersubject variation, modeling inaccuracies) bears one considerable drawback: It often results in over-conservative scanning constraints. We present a more efficient approach to define a variable safety margin based on the conditional probability density function of the effectively obtained pSAR10g value, given the estimated pSAR10g value. METHODS: The conditional probability density function can be estimated from previously simulated data. A representative set of true and estimated pSAR10g samples was generated by means of our database of 23 subject-specific models with an 8-fractionated dipole array for prostate imaging at 7 T. The conditional probability density function was calculated for each possible estimated pSAR10g value and used to determine the corresponding safety margin with an arbitrary low probability of underestimation. This approach was applied to five state-of-the-art local SAR estimation methods, namely: (1) using just the generic body model "Duke"; (2) using our model library to assess the maximum pSAR10g value over all models; (3) using the most representative "local SAR model"; (4) using the five most representative local SAR models; and (5) using a recently developed deep learning-based method. RESULTS: Compared with the more conventional safety factor, the conditional safety-margin approach results in lower (up to 30%) mean overestimation for all investigated local SAR estimation methods. CONCLUSION: The proposed probabilistic approach for pSAR10g correction allows more accurate local SAR assessment with much lower overestimation, while a predefined level of underestimation is accepted (eg, 0.1%).

Local SAR, global SAR, and power-constrained large-flip-angle pulses with optimal control and virtual observation points.

PURPOSE: To present a constrained optimal-control (OC) framework for designing large-flip-angle parallel-transmit (pTx) pulses satisfying hardware peak-power as well as regulatory local and global specific-absorption-rate (SAR) limits. The application is 2D and 3D spatial-selective 90° and 180° pulses. THEORY AND METHODS: The OC gradient-ascent-pulse-engineering method with exact gradients and the limited-memory Broyden-Fletcher-Goldfarb-Shanno method is proposed. Local SAR is constrained by the virtual-observation-points method. Two numerical models facilitated the optimizations, a torso at 3 T and a head at 7 T, both in eight-channel pTx coils and acceleration-factors up to 4. RESULTS: The proposed approach yielded excellent flip-angle distributions. Enforcing the local-SAR constraint, as opposed to peak power alone, reduced the local SAR 7 and 5-fold with the 2D torso excitation and inversion pulse, respectively. The root-mean-square errors of the magnetization profiles increased less than 5% with the acceleration factor of 4. CONCLUSION: A local and global SAR, and peak-power constrained OC large-flip-angle pTx pulse design was presented, and numerically validated for 2D and 3D spatial-selective 90° and 180° pulses at 3 T and 7 T. Magn Reson Med 77:374-384, 2017. © 2015 Wiley Periodicals, Inc.

Effects of Anatomical Differences on Electromagnetic Fields, SAR, and Temperature Change.

Electromagnetic field simulations are increasingly used to assure RF safety of patients during MRI exams. In practice, however, tissue property distribution of the patient being imaged is not known, but may be represented with a pre-existing model. Repeatedly, agreement in transmit magnetic (B1+) field distributions between two geometries has been used to suggest agreement in heating distributions. Here we examine relative effects of anatomical differences on B1+ distribution, Specific Absorption Rate (SAR) and temperature change (ΔT). Numerical simulations were performed for a single surface coil positioned adjacent a homogeneous phantom and bovine phantom, each with slight geometric variations, and adjacent two different human body models. Experimental demonstration was performed on a bovine phantom using MR thermometry and B1+ mapping. Simulations and experiments demonstrate that B1+ distributions in different samples can be well correlated, while notable difference in maximum SAR and ΔT occur. This work illustrates challenges associated with utilizing simulations or experiments for RF safety assurance purposes. Reliance on B1+ distributions alone for validation of simulations and/or experiments with a sample or subject for assurance of safety in another should be performed with caution.

An anatomically realistic temperature phantom for radiofrequency heating measurements.

PURPOSE: An anthropomorphic phantom with realistic electrical properties allows for a more accurate reproduction of tissue current patterns during excitation. A temperature map can then probe the worst-case heating expected in the unperfused case. We describe an anatomically realistic human head phantom that allows rapid three-dimensional (3D) temperature mapping at 7T. METHODS: The phantom was based on hand-labeled anatomical imaging data and consists of four compartments matching the corresponding human tissues in geometry and electrical properties. The increases in temperature resulting from radiofrequency excitation were measured with MR thermometry using a temperature-sensitive contrast agent (TmDOTMA(-)) validated by direct fiber optic temperature measurements. RESULTS: Acquisition of 3D temperature maps of the full phantom with a temperature accuracy better than 0.1°C was achieved with an isotropic resolution of 5 mm and acquisition times of 2-4 minutes. CONCLUSION: Our results demonstrate the feasibility of constructing anatomically realistic phantoms with complex geometries incorporating the ability to measure accurate temperature maps in the phantom. The anthropomorphic temperature phantom is expected to provide a useful tool for the evaluation of the heating effects of both conventional and parallel transmit pulses and help validate electromagnetic and temperature simulations.

A method for safety testing of radiofrequency/microwave-emitting devices using MRI.

PURPOSE: Strict regulations are imposed on the amount of radiofrequency (RF) energy that devices can emit to prevent excessive deposition of RF energy into the body. In this study, we investigated the application of MR temperature mapping and 10-g average specific absorption rate (SAR) computation for safety evaluation of RF-emitting devices. METHODS: Quantification of the RF power deposition was shown for an MRI-compatible dipole antenna and a non-MRI-compatible mobile phone via phantom temperature change measurements. Validation of the MR temperature mapping method was demonstrated by comparison with physical temperature measurements and electromagnetic field simulations. MR temperature measurements alongside physical property measurements were used to reconstruct 10-g average SAR. RESULTS: The maximum temperature change for a dipole antenna and the maximum 10-g average SAR were 1.83°C and 12.4 W/kg, respectively, for simulations and 1.73°C and 11.9 W/kg, respectively, for experiments. The difference between MR and probe thermometry was <0.15°C. The maximum temperature change and the maximum 10-g average SAR for a cell phone radiating at maximum output for 15 min was 1.7°C and 0.54 W/kg, respectively. CONCLUSION: Information acquired using MR temperature mapping and thermal property measurements can assess RF/microwave safety with high resolution and fidelity.

Comparison of simulated parallel transmit body arrays at 3 T using excitation uniformity, global SAR, local SAR, and power efficiency metrics.

PURPOSE: We compare the performance of eight parallel transmit (pTx) body arrays with up to 32 channels and a standard birdcage design. Excitation uniformity, local specific absorption rate (SAR), global SAR, and power metrics are analyzed in the torso at 3 T for radiofrequency (RF)-shimming and 2-spoke excitations. METHODS: We used a fast cosimulation strategy for field calculation in the presence of coupling between transmit channels. We designed spoke pulses using magnitude least squares optimization with explicit constraint of SAR and power and compared the performance of the different pTx coils using the L-curve method. RESULTS: PTx arrays outperformed the conventional birdcage coil in all metrics except peak and average power efficiency. The presence of coupling exacerbated this power efficiency problem. At constant excitation fidelity, the pTx array with 24 channels arranged in three z-rows could decrease local SAR more than 4-fold (2-fold) for RF-shimming (2-spoke) compared to the birdcage coil for pulses of equal duration. Multi-row pTx coils had a marked performance advantage compared to single row designs, especially for coronal imaging. CONCLUSION: PTx coils can simultaneously improve the excitation uniformity and reduce SAR compared to a birdcage coil when SAR metrics are explicitly constrained in the pulse design.

SAR reduction in 7T C-spine imaging using a "dark modes" transmit array strategy.

PURPOSE: Local specific absorption rate (SAR) limits many applications of parallel transmit (pTx) in ultra high-field imaging. In this Note, we introduce the use of an array element, which is intentionally inefficient at generating spin excitation (a "dark mode") to attempt a partial cancellation of the electric field from those elements that do generate excitation. We show that adding dipole elements oriented orthogonal to their conventional orientation to a linear array of conventional loop elements can lower the local SAR hotspot in a C-spine array at 7 T. METHODS: We model electromagnetic fields in a head/torso model to calculate SAR and excitation B1 (+) patterns generated by conventional loop arrays and loop arrays with added electric dipole elements. We utilize the dark modes that are generated by the intentional and inefficient orientation of dipole elements in order to reduce peak 10g local SAR while maintaining excitation fidelity. RESULTS: For B1 (+) shimming in the spine, the addition of dipole elements did not significantly alter the B1 (+) spatial pattern but reduced local SAR by 36%. CONCLUSION: The dipole elements provide a sufficiently complimentary B1 (+) and electric field pattern to the loop array that can be exploited by the radiofrequency shimming algorithm to reduce local SAR.

Parallel transmit pulse design for patients with deep brain stimulation implants.

PURPOSE: Specific absorption rate (SAR) amplification around active implantable medical devices during diagnostic MRI procedures poses a potential risk for patient safety. In this study, we present a parallel transmit (pTx) strategy that can be used to safely scan patients with deep brain stimulation (DBS) implants. METHODS: We performed electromagnetic simulations at 3T using a uniform phantom and a multitissue realistic head model with a generic DBS implant. Our strategy is based on using implant-friendly modes, which are defined as the modes of an array that reduce the local SAR around the DBS lead tip. These modes are used in a spokes pulse design algorithm in order to produce highly uniform magnitude least-squares flip angle excitations. RESULTS: Local SAR (1 g) at the lead tip is reduced below 0.1 W/kg compared with 31.2 W/kg, which is obtained by a simple quadrature birdcage excitation without any sort of SAR mitigation. For the multitissue realistic head model, peak 10 g local SAR and global SAR are obtained as 4.52 W/kg and 0.48 W/kg, respectively. A uniform axial flip angle is also obtained (NRMSE <3%). CONCLUSION: Parallel transmit arrays can be used to generate implant-friendly modes and to reduce SAR around DBS implants while constraining peak local SAR and global SAR and maximizing flip angle homogeneity.

Local specific absorption rate (SAR), global SAR, transmitter power, and excitation accuracy trade-offs in low flip-angle parallel transmit pulse design.

PURPOSE: We propose a constrained optimization approach for designing parallel transmit (pTx) pulses satisfying all regulatory and hardware limits. We study the trade-offs between excitation accuracy, local and global specific absorption rate (SAR), and maximum and average power for small flip-angle pTx (eight channels) spokes pulses in the torso at 3 T and in the head at 7 T. METHODS: We compare the trade-offs between the above-mentioned quantities using the L-curve method. We use a primal-dual algorithm and a compressed set of local SAR matrices to design radio-frequency (RF) pulses satisfying all regulatory (including local SAR) and hardware constraints. RESULTS: Local SAR can be substantially reduced (factor of 2 or more) by explicitly constraining it in the pulse design process compared to constraining global SAR or pulse power alone. This often comes at the price of increased pulse power. CONCLUSION: Simultaneous control of power and SAR is needed for the design of pTx pulses that are safe and can be played on the scanner. Constraining a single quantity can create large increase in the others, which can then rise above safety or hardware limits. Simultaneous constraint of local SAR and power is fast enough to be applicable in a clinical setting.

Parallel transmission 2D RARE imaging at 7T with transmit field inhomogeneity mitigation and local SAR control.

PURPOSE: We develop and test a parallel transmit (pTx) pulse design framework to mitigate transmit field inhomogeneity with control of local specific absorption rate (SAR) in 2D rapid acquisition with relaxation enhancement (RARE) imaging at 7T. METHODS: We design large flip angle RF pulses with explicit local SAR constraints by numerical simulation of the Bloch equations. Parallel computation and analytical expressions for the Jacobian and the Hessian matrices are employed to reduce pulse design time. The refocusing-excitation "spokes" pulse pairs are designed to satisfy the Carr-Purcell-Meiboom-Gill (CPMG) condition using a combined magnitude least squares-least squares approach. RESULTS: In a simulated dataset, the proposed approach reduced peak local SAR by up to 56% for the same level of refocusing uniformity error and reduced refocusing uniformity error by up to 59% (from 32% to 7%) for the same level of peak local SAR compared to the circularly polarized birdcage mode of the pTx array. Using explicit local SAR constraints also reduced peak local SAR by up to 46% compared to an RF peak power constrained design. The excitation and refocusing uniformity error were reduced from 20%-33% to 4%-6% in single slice phantom experiments. Phantom experiments demonstrated good agreement between the simulated excitation and refocusing uniformity profiles and experimental image shading. CONCLUSION: PTx-designed excitation and refocusing CPMG pulse pairs can mitigate transmit field inhomogeneity in the 2D RARE sequence. Moreover, local SAR can be decreased significantly using pTx, potentially leading to better slice coverage, enabling larger flip angles or faster imaging.

7T MR Thermometry technique for validation of system-predicted SAR with a home-built radiofrequency wrist coil.

PURPOSE: A 7T magnetic resonance thermometry (MRT) technique was developed to validate the conversion factor between the system-measured transmitted radiofrequency (RF) power into a home-built RF wrist coil with the system-predicted SAR value. The conversion factor for a new RF coil developed for ultra high magnetic field MRI systems is used to ensure that regulatory limits on RF energy deposition in tissue, specifically the local 10g-averaged specific absorption rate (SAR10g ), are not exceeded. MRT can be used to validate this factor by ensuring that MRT-measured SAR values do not exceed those predicted by the system. METHODS: A 14-cm diameter high-pass birdcage RF coil was built to image the wrist at 7T. A high spatial and temporal resolution dual-echo gradient echo MRT technique, incorporating quasi-simultaneous RF-induced heating and temperature change measurements using the proton resonance frequency method, was developed. The technique allowed for high-temperature resolution measurements (~±0.1°C) to be performed every 20 s over a 4-min heating period, with high spatial resolution (2.56 mm3 voxel size) and avoiding phase discontinuities arising from severe magnetic susceptibility-induced B0 inhomogeneities. Magnetic resonance thermometry was performed on a phantom made from polyvinylpyrrolidone to mimic the dielectric properties of muscle tissue at 297.2 MHz. Temperature changes measured with MRT and four fiber optic temperature sensors embedded in the phantom were compared. Electromagnetic simulations of the coil and phantom were developed and validated via comparison of simulated and measured B1 + maps in the phantom. The position of maximum SAR within the coil was determined from simulations, and MRT was performed within a wrist-sized piece of meat positioned at that SAR hotspot location. MRT-measured and system-predicted SAR values for the phantom and meat were compared. RESULTS: Temperature change measurements from MRT matched closely to those from the fiber optic temperature sensors. The simulations were validated via close correlation between the simulated and MRT-measured B1 + and SAR maps. Using a coil conversion factor of 2 kg-1 , MRT-measured point-SAR values did not exceed the system-predicted SAR10g in either the uniform phantom or in the piece of meat mimicking the wrist located at the SAR hotspot location. CONCLUSIONS: A highly accurate MRT technique with high spatial and temporal resolution was developed. This technique can be used to ensure that system-predicted SAR values are not exceeded in practice, thereby providing independent validation of SAR levels delivered by a newly built RF wrist coil. The MRT technique is readily generalizable to perform safety evaluations for other RF coils at 7T.

B1-control receive array coil (B-RAC) for reducing B1+ inhomogeneity in abdominal imaging at 3T-MRI.

B1+ inhomogeneity in the human body increases as the nuclear magnetic resonance (NMR) frequency increases. Various methods have thus been developed to reduce B1+ inhomogeneity, such as a dielectric pad, a coupling coil, parallel transmit, and radio-frequency (RF) shimming. However, B1+ inhomogeneity still remains in some cases of abdominal imaging. In this study, we developed a B1-control receive array coil (B-RAC). Unlike the conventional receive array coil, B-RAC reduces B1+ inhomogeneity by using additional PIN diodes to generate the inductive loop during the RF transmit period. The inductive loop can generate dense and sparse regions of the magnetic flux, which can be used to compensate for B1+ inhomogeneity. First, B-RAC is modeled in the numerical simulation, and the spatial distributions of B1+ in a phantom and a human model were analyzed. Next, we fabricated a 12-channel B-RAC and measured receive sensitivity and B1+ maps in a 3T-MRI experiment. It was demonstrated that B-RAC can reduce B1+ inhomogeneity in the phantom and human model without increasing the maximum local specific absorption rate (SAR) in the body. B-RAC was also found to have almost the same the receive sensitivity as the conventional receive coil. Using RF shimming combined with B-RAC was revealed to more effectively reduce B1+ inhomogeneity than using only RF shimming. Therefore, B-RAC can reduce B1+ inhomogeneity while maintaining the receive sensitivity.

On the safety margin of using simplified human head models for local SAR simulations of B1-shimming at 7 Tesla.

PURPOSES: Using simplified human models significantly alleviates the difficulty of rendering human models for subject-specific local specific absorption rate (SAR) simulations. Although its accuracy has been demonstrated with the birdcage mode combination of RF transmitters, its accuracy in general B1-shimming, where numerous phase and magnitude combinations can take place, is yet unknown. METHODS: The electromagnetic fields of a 7-Tesla eight-channel brain imaging array were simulated by using four detailed human models from the Virtual Family and their two-, three-, and four-tissue simplifications. The 10-g averaged local SAR was computed for each case with 1,000 sets of uniformly distributed random B1-shimming parameters. Linear regression was applied to relate the local SAR obtained by using detailed and simplified human models. The 99% confidence prediction interval was determined as the safety margin in order to cover the largest local SAR variability introduced by using simplified human models. RESULTS: The local SAR computed by using three- and four-tissue simplifications are strongly correlated with those computed by using detailed models. Safety margins of 0.38 and 0.45W/kg/W were found appropriate for each case being considered. CONCLUSIONS: The proposed procedure can be applied to evaluate the safety margin of the local SAR simulated by using simplified human models. However, discretion needs to be exercised since the safety margins in some cases may represent more than 50% overestimation.