Detalhe da pesquisa
1.
Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone-receptor activation.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290145
2.
'Smart' insulin-delivery technologies and intrinsic glucose-responsive insulin analogues.
Diabetologia
; 64(5): 1016-1029, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33710398
3.
NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion.
Biochim Biophys Acta Biomembr
; 1860(2): 407-415, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28988778
4.
Synthesis of a new ß-amino acid with a 3-deoxy-L-ara furnaoside side chain: the influence of the side chain on the conformation of α/ß-peptides.
Org Biomol Chem
; 14(2): 503-515, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26489370
5.
Synthesis of C-linked carbo-ß2-amino acids and ß2-peptides: design of new motifs for left-handed 12/10- and 10/12-mixed helices.
Org Biomol Chem
; 10(46): 9191-203, 2012 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23089875
6.
New Horizons: Next-Generation Insulin Analogues: Structural Principles and Clinical Goals.
J Clin Endocrinol Metab
; 107(4): 909-928, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34850005
7.
Tenuous transcriptional threshold of human sex determination. II. SRY exploits water-mediated clamp at the edge of ambiguity.
Front Endocrinol (Lausanne)
; 13: 1029177, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36568077
8.
Synthesis and structural studies of homooligomers of geminally disubstituted ß(2,2)-amino acids with carbohydrate side chain.
J Org Chem
; 76(6): 1562-71, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21338140
9.
Structural Lessons From the Mutant Proinsulin Syndrome.
Front Endocrinol (Lausanne)
; 12: 754693, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34659132
10.
Diabetes mellitus due to toxic misfolding of proinsulin variants.
Mol Metab
; : 101229, 2021 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33823319
11.
Structural principles of insulin formulation and analog design: A century of innovation.
Mol Metab
; 52: 101325, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428558
12.
Binary and ternary complexes of FLNa-Ig21 with cytosolic tails of αMß2 integrin reveal dual role of filamin mediated regulation.
Biochim Biophys Acta Gen Subj
; 1865(12): 130005, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509570
13.
Theoretical and experimental studies on alpha/epsilon-hybrid peptides: design of a 14/12-helix from peptides with alternating (S)-C-linked carbo-epsilon-amino acid [(S)-epsilon-Caa((x))] and L-ala.
J Org Chem
; 74(17): 6703-13, 2009 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19663475
14.
NMR Structure, Dynamics and Interactions of the Integrin ß2 Cytoplasmic Tail with Filamin Domain IgFLNa21.
Sci Rep
; 8(1): 5490, 2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29615775
15.
Interaction Analyses of 14-3-3ζ, Dok1, and Phosphorylated Integrin ß Cytoplasmic Tails Reveal a Bi-molecular Switch in Integrin Regulation.
J Mol Biol
; 430(21): 4419-4430, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30243836
16.
Interaction Analyses of the Integrin ß2 Cytoplasmic Tail with the F3 FERM Domain of Talin and 14-3-3ζ Reveal a Ternary Complex with Phosphorylated Tail.
J Mol Biol
; 428(20): 4129-4142, 2016 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27545410