Detalhe da pesquisa
1.
Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma.
Gastroenterology
; 162(4): 1303-1318.e18, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34973294
2.
Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors.
Gene Ther
; 29(3-4): 138-146, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33958732
3.
A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination.
Lab Invest
; 99(8): 1233-1244, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728464
4.
GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.
Gastroenterology
; 155(5): 1593-1607.e12, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30142336
5.
Ablation of Dicer leads to widespread perturbation of signaling pathways.
Biochem Biophys Res Commun
; 463(3): 389-94, 2015 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26032504
6.
Regulation of lipid metabolism by Dicer revealed through SILAC mice.
J Proteome Res
; 11(4): 2193-205, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22313051
7.
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis.
Cancer Cell
; 3(6): 565-76, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12842085
8.
Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma.
Cancers (Basel)
; 13(22)2021 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830866
9.
Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis.
Cancers (Basel)
; 12(9)2020 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967217
10.
Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment.
Cancer Discov
; 10(4): 608-625, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046984
11.
Interactions between hairy/enhancer of split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex.
Biochem J
; 393(Pt 3): 679-85, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16201968
12.
Primary explant cultures of adult and embryonic pancreas.
Methods Mol Med
; 103: 259-71, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15542912
13.
Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.
PLoS One
; 9(11): e113127, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25405615
14.
Regulation of PPAR-alpha pathway by Dicer revealed through proteomic analysis.
J Proteomics
; 108: 306-15, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24769236
15.
p53: Guardian of pancreatic epithelial identity.
Cell Cycle
; 10(11): 1717, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21597331
16.
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.
Dev Biol
; 274(2): 491-503, 2004 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15570689
17.
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.
Dev Biol
; 270(2): 474-86, 2004 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15183727
18.
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas.
Development
; 131(17): 4213-24, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15280211