Detalhe da pesquisa
1.
Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma.
Blood
; 140(23): 2463-2476, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960849
2.
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.
Blood
; 137(6): 801-811, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32812017
3.
TAL1 cooperates with PI3K/AKT pathway activation in T-cell acute lymphoblastic leukemia.
Haematologica
; 107(10): 2304-2317, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35354248
4.
Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping.
Am J Hematol
; 97(5): 548-561, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35119131
5.
Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.
Blood
; 134(16): 1323-1336, 2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492675
6.
Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL.
Blood
; 131(4): 421-425, 2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29187379
7.
Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.
Blood
; 128(23): 2642-2654, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694322
8.
Combination therapy of a PSEN1-selective γ-secretase inhibitor with dexamethasone and an XPO1 inhibitor to target T-cell acute lymphoblastic leukemia.
Haematologica
; 108(9): 2507-2512, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36700404
9.
Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
J Biol Chem
; 290(48): 29022-34, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446793
10.
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.
Blood
; 124(20): 3092-100, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193870
11.
Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.
Mol Cell
; 31(1): 134-42, 2008 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18614052
12.
Development of a siRNA and shRNA screening system based on a kinase fusion protein.
RNA
; 18(6): 1296-306, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539522
13.
NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.
Haematologica
; 99(1): 85-93, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23872305
14.
JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma.
Blood
; 117(15): 4056-64, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325169
15.
Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing.
Hemasphere
; 6(4): e700, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35291210
16.
PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.
J Hematol Oncol
; 14(1): 97, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34167562
17.
Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified.
Nat Commun
; 12(1): 3705, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140493
18.
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires ß-catenin activity to drive T-cell acute lymphoblastic leukemia.
Nat Commun
; 12(1): 4164, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34230493
19.
The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.
Clin Cancer Res
; 26(21): 5747-5758, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32826328
20.
The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models.
J Hematol Oncol
; 11(1): 108, 2018 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30144809