Detalhe da pesquisa
1.
Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages.
Eur Respir J
; 54(4)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320451
2.
The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition.
Exp Dermatol
; 28(1): 3-10, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30332502
3.
Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists.
Am J Respir Crit Care Med
; 198(6): 739-750, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29547002
4.
Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline.
Thorax
; 72(5): 400-408, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28174340
5.
Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.
PLoS Genet
; 10(5): e1004314, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24786987
6.
Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium.
J Antimicrob Chemother
; 71(10): 2767-81, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27494903
7.
Glycogen synthase kinase-3ß modulation of glucocorticoid responsiveness in COPD.
Am J Physiol Lung Cell Mol Physiol
; 309(10): L1112-23, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26320152
8.
Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes.
J Immunol
; 190(4): 1551-9, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319734
9.
Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects.
Eur J Clin Pharmacol
; 71(10): 1175-84, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26265232
10.
Quantifying Cell Death Induced by the NLRC4 Inflammasome.
Methods Mol Biol
; 2696: 199-210, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37578724
11.
Fragment based discovery of a novel and selective PI3 kinase inhibitor.
Bioorg Med Chem Lett
; 21(21): 6586-90, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21925880
12.
Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function.
Respiration
; 81(6): 499-510, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21430361
13.
The Interleukin-1 Receptor-Associated Kinase 4 Inhibitor PF-06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial.
Arthritis Rheumatol
; 73(12): 2206-2218, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423919
14.
JAK-STAT pathway activation in COPD.
Eur Respir J
; 46(3): 843-5, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26113679
15.
Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study.
BMC Med Genet
; 11: 152, 2010 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21044285
16.
Safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06650833, a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, in single and multiple ascending dose randomized phase 1 studies in healthy subjects.
Arthritis Res Ther
; 21(1): 269, 2019 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31805989
17.
PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor.
ACS Chem Biol
; 14(6): 1235-1242, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31082193
18.
Improved image analysis workflow for 2-D gels enables large-scale 2-D gel-based proteomics studies--COPD biomarker discovery study.
Proteomics
; 8(15): 3030-41, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18618493
19.
Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function.
Wellcome Open Res
; 3: 13, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29682616
20.
The role of IFN-gamma in regulation of IFN-gamma-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures.
Respir Res
; 8: 80, 2007 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17996064