Detalhe da pesquisa
1.
Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors.
BMC Genomics
; 21(1): 2, 2020 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31898484
2.
A CD3-bispecific molecule targeting P-cadherin demonstrates T cell-mediated regression of established solid tumors in mice.
Cancer Immunol Immunother
; 67(2): 247-259, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29067496
3.
Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186.
J Immunother Cancer
; 10(6)2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728872
4.
Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade.
Mol Cancer Ther
; 21(9): 1462-1472, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35793468
5.
Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model.
Oncotarget
; 11(15): 1344-1357, 2020 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32341754
6.
COBRA™: a highly potent conditionally active T cell engager engineered for the treatment of solid tumors.
MAbs
; 12(1): 1792130, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32684124
7.
Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling.
J Clin Invest
; 115(11): 2992-3006, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16224539
8.
Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes.
Nat Biotechnol
; 21(4): 405-13, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12652311
9.
Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin.
Clin Cancer Res
; 11(13): 4934-40, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16000592
10.
Limited proliferation and telomere dysfunction following telomerase inhibition in immortal murine fibroblasts.
Cancer Res
; 62(7): 2104-14, 2002 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11929832
11.
Combining antibody-drug conjugates and immune-mediated cancer therapy: What to expect?
Biochem Pharmacol
; 102: 1-6, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26686577
12.
Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Antibodies (Basel)
; 5(1)2016 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557987
13.
Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras.
Oncogene
; 21(27): 4200-11, 2002 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12082607
14.
Progress toward the genetic treatment of the beta-thalassemias.
Ann N Y Acad Sci
; 1054: 78-91, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16339654
15.
Advances in bispecific biotherapeutics for the treatment of cancer.
Biochem Pharmacol
; 84(9): 1105-12, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22858161
16.
Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes.
Int J Nanomedicine
; 5: 783-802, 2010 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21042424
17.
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Cell Stem Cell
; 6(3): 251-64, 2010 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20207228
18.
Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.
J Natl Cancer Inst
; 102(12): 894-908, 2010 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20463307
19.
Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization.
PLoS One
; 2(3): e267, 2007 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-17342201
20.
Methotrexate preconditioning allows sufficient engraftment to confer drug resistance in mice transplanted with marrow expressing drug-resistant dihydrofolate reductase activity.
J Pharmacol Exp Ther
; 314(2): 668-74, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15857949