Detalhe da pesquisa
1.
Reducing affinity as a strategy to boost immunomodulatory antibody agonism.
Nature
; 614(7948): 539-547, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36725933
2.
Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function.
Immunity
; 49(5): 958-970.e7, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446386
3.
Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412.
Blood
; 125(1): 102-10, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25395427
4.
Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.
Blood
; 125(12): 1901-9, 2015 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631769
5.
Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors.
J Immunol
; 195(11): 5503-16, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26512139
6.
Fcγ receptor dependency of agonistic CD40 antibody in lymphoma therapy can be overcome through antibody multimerization.
J Immunol
; 193(4): 1828-35, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25024386
7.
Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia.
Blood
; 119(7): 1726-36, 2012 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22160382
8.
Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells.
Blood
; 119(1): 170-9, 2012 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22086413
9.
Development and characterisation of monoclonal antibodies specific for the murine inhibitory FcγRIIB (CD32B).
Eur J Immunol
; 42(8): 2109-20, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22760702
10.
Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.
Blood
; 118(9): 2530-40, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21768293
11.
Interaction with FcγRIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody.
J Immunol
; 187(4): 1754-63, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21742972
12.
Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc.
Front Immunol
; 14: 1252274, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37965342
13.
The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL.
Blood
; 115(1): 71-7, 2010 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19887677
14.
Anti-mouse FcγRIV antibody 9E9 also blocks FcγRIII in vivo.
Blood
; 126(24): 2643-5, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26492935
15.
Surface IgM of CLL cells displays unusual glycans indicative of engagement of antigen in vivo.
Blood
; 115(21): 4198-205, 2010 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20237321
16.
Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments.
J Immunother Cancer
; 10(1)2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017153
17.
Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering.
Commun Biol
; 5(1): 229, 2022 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35288635
18.
FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms.
Cell Rep
; 40(3): 111099, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858562
19.
TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity.
Commun Biol
; 4(1): 772, 2021 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162985
20.
FcγRII (CD32) modulates antibody clearance in NOD SCID mice leading to impaired antibody-mediated tumor cell deletion.
J Immunother Cancer
; 8(1)2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554613