Detalhe da pesquisa
1.
Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1.
Blood
; 123(4): 509-19, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24184684
2.
The localization, origin, and impact of platelets in the tumor microenvironment are tumor type-dependent.
J Exp Clin Cancer Res
; 43(1): 84, 2024 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493157
3.
From normal hematopoiesis to malignancies: Highlights from the 2021 Meeting of the Club Hematopoiesis and Oncogenesis.
Bull Cancer
; 110(3): 331-335, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36775700
4.
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice.
Leukemia
; 37(6): 1287-1297, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37100881
5.
The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis.
Blood
; 115(18): 3686-94, 2010 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20223923
6.
NF-κB signaling controls H3K9me3 levels at intronic LINE-1 and hematopoietic stem cell genes in cis.
J Exp Med
; 219(8)2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802137
7.
Macrophage migration inhibitory factor is overproduced through EGR1 in TET2low resting monocytes.
Commun Biol
; 5(1): 110, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35115654
8.
Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.
Stem Cells
; 27(9): 2153-62, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19522008
9.
p-ERK1/2 is a predictive factor of response to erythropoiesis-stimulating agents in low/int-1 myelodysplastic syndromes.
Haematologica
; 95(11): 1964-8, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20823131
10.
Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response.
J Exp Med
; 215(5): 1463-1480, 2018 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29615469
11.
The cancer chemopreventive agent resveratrol induces tensin, a cell-matrix adhesion protein with signaling and antitumor activities.
Oncogene
; 24(20): 3274-84, 2005 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15735708
12.
Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.
Stem Cell Reports
; 6(6): 970-984, 2016 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27304919
13.
Development of T-cell lymphomas in Emu-IEX-1 mice.
Oncogene
; 22(44): 6845-51, 2003 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14534530
14.
IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.
J Clin Invest
; 124(11): 4709-22, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25250570
15.
Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.
EMBO Mol Med
; 6(6): 821-34, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24778454
16.
Thrombopoietin-increased DNA-PK-dependent DNA repair limits hematopoietic stem and progenitor cell mutagenesis in response to DNA damage.
Cell Stem Cell
; 12(1): 37-48, 2013 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23246483
17.
ERK1 regulates the hematopoietic stem cell niches.
PLoS One
; 7(1): e30788, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22303456
18.
Inhibition of B56-containing protein phosphatase 2As by the early response gene IEX-1 leads to control of Akt activity.
J Biol Chem
; 282(8): 5468-77, 2007 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17200115
19.
B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK.
EMBO J
; 25(4): 727-38, 2006 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16456541
20.
Thrombopoietin regulates IEX-1 gene expression through ERK-induced AML1 phosphorylation.
Blood
; 107(8): 3106-13, 2006 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368886