Detalhe da pesquisa
1.
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects.
Diabetes Obes Metab
; 25(3): 856-877, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36495318
2.
A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models.
Diabetes Obes Metab
; 22(10): 1729-1741, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32410372
3.
Corrination mitigates peptide aggregation as exemplified for Glucagon.
Peptides
; 171: 171134, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092266
4.
Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced Malaise.
J Med Chem
; 66(16): 11237-11249, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37506293
5.
Glucagon-like peptide-1 in diabetes care: Can glycaemic control be achieved without nausea and vomiting?
Br J Pharmacol
; 179(4): 542-556, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34363224
6.
Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4.
J Med Chem
; 64(6): 3479-3492, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33677970
7.
Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis.
Cell Rep
; 31(11): 107768, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32553160
8.
Mapping the structural boundaries of quasiracemate fractional crystallization using 2-substituted diarylamides.
Chem Commun (Camb)
; 53(33): 4601-4604, 2017 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28394385