Detalhe da pesquisa
1.
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Nature
; 593(7860): 597-601, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33902106
2.
Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML.
Blood
; 141(9): 1023-1035, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35981498
3.
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals.
Blood
; 140(10): 1104-1118, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35878001
4.
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1.
Blood
; 140(24): 2594-2610, 2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857899
5.
Combined proteomics and CRISPRâCas9 screens in PDX identify ADAM10 as essential for leukemia in vivo.
Mol Cancer
; 22(1): 107, 2023 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37422628
6.
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
Blood
; 138(25): 2655-2669, 2021 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280257
7.
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.
Blood
; 136(12): 1407-1418, 2020 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483603
8.
Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML.
Blood
; 134(3): 263-276, 2019 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31076446
9.
WT1 and DNMT3A play essential roles in the growth of certain patient AML cells in mice.
Blood
; 141(8): 955-960, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36256915
10.
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics.
Haematologica
; 104(3): 546-555, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30309851
11.
Plasticity in growth behavior of patients' acute myeloid leukemia stem cells growing in mice.
Haematologica
; 105(12): 2855-2860, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33256387
12.
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
Nat Biotechnol
; 41(11): 1618-1632, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914885
13.
A Novel Anti-CD73 Antibody That Selectively Inhibits Membrane CD73 Shows Antitumor Activity and Induces Tumor Immune Escape.
Biomedicines
; 10(4)2022 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35453575
14.
Adverse stem cell clones within a single patient's tumor predict clinical outcome in AML patients.
J Hematol Oncol
; 15(1): 25, 2022 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35279202
15.
Prime-seq, efficient and powerful bulk RNA sequencing.
Genome Biol
; 23(1): 88, 2022 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35361256
16.
Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.
Leukemia
; 36(10): 2396-2407, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35999260
17.
Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice.
Hepatology
; 51(4): 1226-36, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20099303
18.
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
J Hematol Oncol
; 14(1): 155, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34579739
19.
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
Sci Rep
; 11(1): 5838, 2021 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33712646
20.
In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets.
Nat Commun
; 12(1): 5655, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34580292