Detalhe da pesquisa
1.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Cell
; 164(5): 896-910, 2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26919428
2.
Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.
J Pharmacol Exp Ther
; 386(2): 242-258, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37308266
3.
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
J Hepatol
; 74(1): 156-167, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32763266
4.
NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice.
Hepatology
; 69(2): 845-859, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30180270
5.
Enteroids expressing a disease-associated mutant of EpCAM are a model for congenital tufting enteropathy.
Am J Physiol Gastrointest Liver Physiol
; 317(5): G580-G591, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31433211
6.
NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.
Hepatology
; 67(2): 736-749, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28902427
7.
Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate.
J Immunol
; 198(8): 3017-3022, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275141
8.
GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation.
Proc Natl Acad Sci U S A
; 113(46): 13132-13137, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799535
9.
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.
Immunity
; 30(6): 875-87, 2009 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19501000
10.
Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10-Dependent Mechanism.
J Immunol
; 195(2): 488-97, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26056255
11.
NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.
FASEB J
; 29(4): 1269-79, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25477279
12.
ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.
J Immunol
; 192(8): 3475-87, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24623133
13.
NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.
Hepatology
; 59(3): 898-910, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23813842
14.
Functional consequences of EpCam mutation in mice and men.
Am J Physiol Gastrointest Liver Physiol
; 306(4): G278-88, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24337010
15.
Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse models.
J Immunol
; 189(6): 2707-11, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22904305
16.
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Sci Rep
; 13(1): 13524, 2023 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37598239
17.
The effect of a fennel seed extract on the STAT signaling and intestinal barrier function.
PLoS One
; 17(7): e0271045, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802574
18.
ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
JCI Insight
; 5(2)2020 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31996485
19.
Mutations in topoisomerase IIß result in a B cell immunodeficiency.
Nat Commun
; 10(1): 3644, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409799
20.
Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Sci Rep
; 13(1): 20081, 2023 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37973811