Pesquisa | Biblioteca Virtual em Saúde Fiocruz

1.

Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease.

Rojas-Quintero, Joselyn; Ochsner, Scott A; New, Felicia; Divakar, Prajan; Yang, Chen Xi; Wu, Tianshi David; Robinson, Jerid; Chandrashekar, Darshan Shimoga; Banovich, Nicholas E; Rosas, Ivan O; Sauler, Maor; Kheradmand, Farrah; Gaggar, Amit; Margaroli, Camilla; San Jose Estepar, Raul; McKenna, Neil J; Polverino, Francesca.

Am J Respir Crit Care Med ; 209(1): 48-58, 2024 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-37934672

2.

Spatial Transcriptomics Resolve an Emphysema-specific Lymphoid Follicle B Cell Signature in COPD.

Rojas-Quintero, Joselyn; Ochsner, Scott A; New, Felicia; Divakar, Prajan; Yang, Chen Xi; Wu, Tianshi David; Robinson, Jerid; Shimoga Chandrashekar, Darshan; Banovich, Nicholas E; Rosas, Ivan O; Sauler, Maor; Kheradmand, Farrah; Gaggar, Amit; Margaroli, Camilla; San Jose Estepar, Raul; McKenna, Neil J; Polverino, Francesca.

Am J Respir Crit Care Med ; 2023 Dec 08.

Artigo em Inglês | MEDLINE | ID: mdl-38064378

3.

SnapShot: NR coregulators.

McKenna, Neil J; O'Malley, Bert W.

Cell ; 143(1): 172-172.e1, 2010 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-20887900

4.

SnapShot: Nuclear receptors II.

McKenna, Neil J; O'Malley, Bert W.

Cell ; 142(6): 986.e1, 2010 Sep 17.

Artigo em Inglês | MEDLINE | ID: mdl-20850017

5.

SnapShot: Nuclear receptors I.

McKenna, Neil J; O'Malley, Bert W.

Cell ; 142(5): 822-822.e1, 2010 Sep 03.

Artigo em Inglês | MEDLINE | ID: mdl-20813267

6.

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop.

Jagodnik, Kathleen M; Koplev, Simon; Jenkins, Sherry L; Ohno-Machado, Lucila; Paten, Benedict; Schurer, Stephan C; Dumontier, Michel; Verborgh, Ruben; Bui, Alex; Ping, Peipei; McKenna, Neil J; Madduri, Ravi; Pillai, Ajay; Ma'ayan, Avi.

J Biomed Inform ; 71: 49-57, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28501646

7.

Research Resources for Nuclear Receptor Signaling Pathways.

McKenna, Neil J.

Mol Pharmacol ; 90(2): 153-9, 2016 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-27216565

8.

Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress.

Taylor, Bethany C; Steinthal, Loic H; Dias, Michelle; Yalamanchili, Hari K; Ochsner, Scott A; Zapata, Gladys E; Mehta, Nitesh R; McKenna, Neil J; Young, Nicolas L; Nuotio-Antar, Alli M.

bioRxiv ; 2024 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-38328142

9.

Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress.

Taylor, Bethany C; Steinthal, Loic H; Dias, Michelle; Yalamanchili, Hari Krishna; Ochsner, Scott A; Zapata, Gladys E; Mehta, Nitesh R; McKenna, Neil J; Young, Nicolas L; Nuotio-Antar, Alli M.

Epigenetics Chromatin ; 17(1): 12, 2024 Apr 27.

Artigo em Inglês | MEDLINE | ID: mdl-38678237

10.

Activation of NF-κB protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish.

Pradhan, Ajay; Khalaf, Hazem; Ochsner, Scott A; Sreenivasan, Rajini; Koskinen, Jarno; Karlsson, Marie; Karlsson, Jesper; McKenna, Neil J; Orbán, László; Olsson, Per-Erik.

J Biol Chem ; 287(45): 37926-38, 2012 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-22988238

11.

Androgen receptor agonism promotes an osteogenic gene program in preadipocytes.

Hartig, Sean M; Feng, Qin; Ochsner, Scott A; Xiao, Rui; McKenna, Neil J; McGuire, Sean E; He, Bin.

Biochem Biophys Res Commun ; 434(2): 357-62, 2013 May 03.

Artigo em Inglês | MEDLINE | ID: mdl-23567971

12.

IL17A Blockade with Ixekizumab Suppresses MuvB Signaling in Clinical Psoriasis.

Ochsner, Scott A; Pedroza, Mesias; Pillich, Rudolf T; Krishnan, Venkatesh; Konicek, Bruce W; Dow, Ernst R; Park, So Young; Agarwal, Sandeep K; McKenna, Neil J.

J Invest Dermatol ; 143(9): 1689-1699, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-36967086

13.

SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8⁺ T cells.

Celada, Sherly I; Lim, Clarice X; Carisey, Alexandre F; Ochsner, Scott A; Arce Deza, Carlos F; Rexie, Praveen; Poli De Frias, Fernando; Cardenas-Castillo, Rafael; Polverino, Francesca; Hengstschläger, Markus; Tsoyi, Konstantin; McKenna, Neil J; Kheradmand, Farrah; Weichhart, Thomas; Rosas, Ivan O; Van Kaer, Luc; Celada, Lindsay J.

Sci Transl Med ; 15(713): eade2581, 2023 09 13.

Artigo em Inglês | MEDLINE | ID: mdl-37703351

14.

Vitamin B2 enables regulation of fasting glucose availability.

Masschelin, Peter M; Saha, Pradip; Ochsner, Scott A; Cox, Aaron R; Kim, Kang Ho; Felix, Jessica B; Sharp, Robert; Li, Xin; Tan, Lin; Park, Jun Hyoung; Wang, Liping; Putluri, Vasanta; Lorenzi, Philip L; Nuotio-Antar, Alli M; Sun, Zheng; Kaipparettu, Benny Abraham; Putluri, Nagireddy; Moore, David D; Summers, Scott A; McKenna, Neil J; Hartig, Sean M.

Elife ; 122023 Jul 07.

Artigo em Inglês | MEDLINE | ID: mdl-37417957

15.

Transcriptomine, a web resource for nuclear receptor signaling transcriptomes.

Ochsner, Scott A; Watkins, Christopher M; McOwiti, Apollo; Xu, Xueping; Darlington, Yolanda F; Dehart, Michael D; Cooney, Austin J; Steffen, David L; Becnel, Lauren B; McKenna, Neil J.

Physiol Genomics ; 44(17): 853-63, 2012 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-22786849

16.

Discovery-driven research and bioinformatics in nuclear receptor and coregulator signaling.

McKenna, Neil J.

Biochim Biophys Acta ; 1812(8): 808-17, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21029773

17.

Transcriptional regulatory networks of circulating immune cells in type 1 diabetes: A community knowledgebase.

Ochsner, Scott A; Pillich, Rudolf T; Rawool, Deepali; Grethe, Jeffrey S; McKenna, Neil J.

iScience ; 25(7): 104581, 2022 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-35832893

18.

Conserved immunomodulatory transcriptional networks underlie antipsychotic-induced weight gain.

Zapata, Rizaldy C; Chaudry, Besma S; Valencia, Mariela Lopez; Zhang, Dinghong; Ochsner, Scott A; McKenna, Neil J; Osborn, Olivia.

Transl Psychiatry ; 11(1): 405, 2021 07 22.

Artigo em Inglês | MEDLINE | ID: mdl-34294678

19.

Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice.

Chen, Ke Yun; De Angulo, Alejandra; Guo, Xin; More, Aditya; Ochsner, Scott A; Lopez, Eduardo; Saul, David; Pang, Weijun; Sun, Yuxiang; McKenna, Neil J; Tong, Qiang.

Front Aging ; 2: 803482, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-35822007

20.

Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs.

Nikolai, Bryan C; Jain, Prashi; Cardenas, David L; York, Brian; Feng, Qin; McKenna, Neil J; Dasgupta, Subhamoy; Lonard, David M; O'Malley, Bert W.

Sci Rep ; 11(1): 3441, 2021 02 09.

Artigo em Inglês | MEDLINE | ID: mdl-33564037

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Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease.

Spatial Transcriptomics Resolve an Emphysema-specific Lymphoid Follicle B Cell Signature in COPD.

SnapShot: NR coregulators.

SnapShot: Nuclear receptors II.

SnapShot: Nuclear receptors I.

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop.

Research Resources for Nuclear Receptor Signaling Pathways.

Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress.

Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress.

Activation of NF-κB protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish.

Androgen receptor agonism promotes an osteogenic gene program in preadipocytes.

IL17A Blockade with Ixekizumab Suppresses MuvB Signaling in Clinical Psoriasis.

SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8⁺ T cells.

Vitamin B2 enables regulation of fasting glucose availability.

Transcriptomine, a web resource for nuclear receptor signaling transcriptomes.

Discovery-driven research and bioinformatics in nuclear receptor and coregulator signaling.

Transcriptional regulatory networks of circulating immune cells in type 1 diabetes: A community knowledgebase.

Conserved immunomodulatory transcriptional networks underlie antipsychotic-induced weight gain.

Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice.

Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs.