RESUMO
PURPOSE: Radiofrequency field inhomogeneity is a significant issue in imaging large fields of view in high- and ultrahigh-field MRI. Passive shimming with coupled coils or dielectric pads is the most common approach at 3 T. We introduce and test light and compact metasurface, providing the same homogeneity improvement in clinical abdominal imaging at 3 T as a conventional dielectric pad. METHODS: The metasurface comprising a periodic structure of copper strips and parallel-plate capacitive elements printed on a flexible polyimide substrate supports propagation of slow electromagnetic waves similar to a high-permittivity slab. We compare the metasurface operating inside a transmit body birdcage coil to the state-of-the-art pad by numerical simulations and in vivo study on healthy volunteers. RESULTS: Numerical simulations with different body models show that the local minimum of B1+ causing a dark void in the abdominal domain is removed by the metasurface with comparable resulting homogeneity as for the pad with decreasing maximum and whole-body SAR values. In vivo results confirm similar homogeneity improvement and demonstrate the stability to body mass index. CONCLUSION: The light, flexible, and inexpensive metasurface can replace a relatively heavy and expensive pad based on the aqueous suspension of barium titanate in abdominal imaging at 3 T.
Assuntos
Imageamento por Ressonância Magnética , Ondas de Rádio , Abdome/diagnóstico por imagem , Simulação por Computador , Humanos , Imagens de FantasmasRESUMO
The study objective was to investigate the performance of a dedicated convolutional neural network (CNN) optimized for wrist cartilage segmentation from 2D MR images. CNN utilized a planar architecture and patch-based (PB) training approach that ensured optimal performance in the presence of a limited amount of training data. The CNN was trained and validated in 20 multi-slice MRI datasets acquired with two different coils in 11 subjects (healthy volunteers and patients). The validation included a comparison with the alternative state-of-the-art CNN methods for the segmentation of joints from MR images and the ground-truth manual segmentation. When trained on the limited training data, the CNN outperformed significantly image-based and PB-U-Net networks. Our PB-CNN also demonstrated a good agreement with manual segmentation (Sørensen-Dice similarity coefficient [DSC] = 0.81) in the representative (central coronal) slices with a large amount of cartilage tissue. Reduced performance of the network for slices with a very limited amount of cartilage tissue suggests the need for fully 3D convolutional networks to provide uniform performance across the joint. The study also assessed inter- and intra-observer variability of the manual wrist cartilage segmentation (DSC = 0.78-0.88 and 0.9, respectively). The proposed deep learning-based segmentation of the wrist cartilage from MRI could facilitate research of novel imaging markers of wrist osteoarthritis to characterize its progression and response to therapy.
Assuntos
Cartilagem/diagnóstico por imagem , Aprendizado Profundo , Imageamento por Ressonância Magnética/métodos , Redes Neurais de Computação , Punho , Adulto , Idoso , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Masculino , Pessoa de Meia-Idade , Osteoartrite/diagnóstico por imagem , Reprodutibilidade dos TestesRESUMO
PURPOSE: To design and test an RF-coil based on two orthogonal eigenmodes in a pair of coupled dipoles, for 7 Tesla body imaging with improved SAR, called dual-mode dipole. METHODS: The proposed coil consists of two dipoles and creates two orthogonal field distributions in a sample (the even and odd modes). A coupler used to excite the modes was miniaturized with the conductor track routing technique. Numerical simulations of the dual-mode dipole in the presence of a homogeneous phantom were performed. Moreover, an array of such coils was simulated with a voxel body model. For comparison, a fractionated dipole combined with a surface loop coil was also simulated. Both coils were tested in a 7 Tesla MRI system on a phantom. Subsequently four dual-mode dipoles or dipole/loop combinations were used for a comparison of imaging performance in a human volunteer. RESULTS: Using the even mode of the dual-mode dipole showed 70% SAR reduction in comparison to the fractionated dipole while having the same B 1 + in the prostate region. The odd mode of the dual-mode dipole showed a performance comparable to the surface loop both for SAR and B1 efficiency. The obtained results showed that the proposed coil while creating lower SAR gave images of the same quality as the reference coil. CONCLUSIONS: It was demonstrated that the array of dual-mode dipoles provided the same SNR and prostate imaging quality as the reference array, while demonstrating lower SAR. This is due to a smoother current distribution over a sample surface.
Assuntos
Imageamento por Ressonância Magnética , Próstata/diagnóstico por imagem , Ondas de Rádio , Algoritmos , Simulação por Computador , Campos Eletromagnéticos , Desenho de Equipamento , Voluntários Saudáveis , Humanos , Masculino , Imagens de Fantasmas , Reprodutibilidade dos Testes , Software , Propriedades de Superfície , Interface Usuário-ComputadorRESUMO
PURPOSE: Design and characterization of a new inductively driven wireless coil (WLC) for wrist imaging at 1.5 T with high homogeneity operating due to focusing the B1 field of a birdcage body coil. METHODS: The WLC design has been proposed based on a volumetric self-resonant periodic structure of inductively coupled split-loop resonators with structural capacitance. The WLC was optimized and studied regarding radiofrequency fields and interaction to the birdcage coil (BC) by electromagnetic simulations. The manufactured WLC was characterized by on-bench measurements and in vivo and phantom study in comparison to a standard cable-connected receive-only coil. RESULTS: The WLC placed into BC gave the measured B1+ increase of the latter by 8.6 times for the same accepted power. The phantom and in vivo wrist imaging showed that the BC in receiving with the WLC inside reached equal or higher signal-to-noise ratio than the conventional clinical setup comprising the transmit-only BC and a commercial receive-only flex-coil and created no artifacts. Simulations and on-bench measurements proved safety in terms of specific absorption rate and reflected transmit power. CONCLUSIONS: The results showed that the proposed WLC could be an alternative to standard cable-connected receive coils in clinical magnetic resonance imaging. As an example, with no cable connection, the WLC allowed wrist imaging on a 1.5 T clinical machine using a full-body BC for transmitting and receive with the desired signal-to-noise ratio, image quality, and safety.
Assuntos
Imageamento por Ressonância Magnética/instrumentação , Imageamento por Ressonância Magnética/métodos , Tecnologia sem Fio/instrumentação , Punho/diagnóstico por imagem , Desenho de Equipamento , Humanos , Processamento de Imagem Assistida por Computador/métodos , Imagens de Fantasmas , Ondas de Rádio , Razão Sinal-RuídoRESUMO
Particular applications in preclinical magnetic resonance imaging require the entire body of an animal to be imaged with sufficient quality. This is usually performed by combining regions scanned with small coils with high sensitivity or long scans using large coils with low sensitivity. Here, a metamaterial-inspired design employing a parallel array of wires operating on the principle of eigenmode hybridization was used to produce a small-animal imaging coil. The coil field distribution responsible for the coil field of view and sensitivity was simulated in an electromagnetic simulation package and the coil geometrical parameters were optimized for whole-body imaging. A prototype coil was then manufactured and assembled using brass telescopic tubes with copper plates as distributed capacitance. Its field distribution was measured experimentally using the B1+ mapping technique and was found to be in close correspondence with the simulated results. The coil field distribution was found to be suitable for large field of view small-animal imaging and the coil image quality was compared with a commercially available coil by whole-body scanning of living mice. Signal-to-noise measurements in living mice showed higher values than those of a commercially available coil with large receptive fields, and rivalled the performance of small receptive field and high-sensitivity coils. The coil was deemed to be suitable for some whole-body, small-animal preclinical applications.
Assuntos
Imageamento por Ressonância Magnética/instrumentação , Ondas de Rádio , Imagem Corporal Total , Animais , Simulação por Computador , Rim/diagnóstico por imagem , Camundongos Endogâmicos BALB C , Razão Sinal-RuídoRESUMO
In this work, we propose an application of high permittivity materials (HPMs) to improve functional magnetic resonance imaging (fMRI) at 1.5 T, increasing the receive (Rx) sensitivity of a commercial multi-channel head coil. To evaluate the transmit efficiency, specific absorption rate (SAR), and the signal-to-noise ratio (SNR) changes introduced by the HPMs with relative permittivity of 4500, we considered the following configurations in simulation: a whole-body birdcage coil and an Rx-only multi-channel head coil with and without the HPM blocks in the presence of a homogeneous head phantom or a human body model. Experimental studies were also performed with a phantom and with volunteers. Seven healthy volunteers enrolled in a prospective study of fMRI activation in the motor cortex with and without HPMs. fMRI data were analyzed using group-level paired T-tests between acquisitions with and without HPM blocks. Both electromagnetic simulations and experimental measurements showed â¼25% improvement in the Rx sensitivity of a commercial head coil in the areas of interest when HPM blocks were placed in close proximity. It increased the detected motor cortex fMRI activation volume by an average of 56%, thus resulting in more sensitive functional imaging at 1.5 T.
Assuntos
Cerâmica , Imageamento por Ressonância Magnética , Humanos , Imageamento por Ressonância Magnética/métodos , Estudos Prospectivos , Desenho de Equipamento , Simulação por Computador , Razão Sinal-Ruído , Imagens de FantasmasRESUMO
Currently, human magnetic resonance (MR) examinations are becoming highly specialized with a pre-defined and often relatively small target in the body. Conventionally, clinical MR equipment is designed to be universal that compromises its efficiency for small targets. Here, we present a concept for targeted clinical magnetic resonance imaging (MRI), which can be directly integrated into the existing clinical MR systems, and demonstrate its feasibility for breast imaging. The concept comprises spatial redistribution and passive focusing of the radiofrequency magnetic flux with the aid of an artificial resonator to maximize the efficiency of a conventional MR system for the area of interest. The approach offers the prospect of a targeted MRI and brings novel opportunities for high quality specialized MR examinations within any existing MR system.
Assuntos
Neoplasias da Mama/diagnóstico por imagem , Cerâmica/efeitos da radiação , Espectroscopia Dielétrica/métodos , Imageamento por Ressonância Magnética/métodos , Espectroscopia de Ressonância Magnética/métodos , Adulto , Cerâmica/química , Espectroscopia Dielétrica/instrumentação , Radiação Eletromagnética , Desenho de Equipamento , Feminino , Voluntários Saudáveis , Humanos , Imageamento por Ressonância Magnética/instrumentação , Imagens de Fantasmas , Razão Sinal-RuídoRESUMO
In this paper, we propose, design and test a new dual-nuclei RF-coil inspired by wire metamaterial structures. The coil operates as a result of resonant excitation of hybridized eigenmodes in multimode flat periodic structures comprising several coupled thin metal strips. It was shown that the field distribution of the coil (i.e. penetration depth) can be controlled independently at two different Larmor frequencies by selecting a proper eigenmode in each of two mutually orthogonal periodic structures. The proposed coil requires no lumped capacitors to be tuned and matched. In order to demonstrate the performance of the new design, an experimental preclinical coil for 19F/1H imaging of small animals at 7.05T was engineered and tested on a homogeneous liquid phantom and in-vivo. The results demonstrate that the coil was both well tuned and matched at two Larmor frequencies and allowed image acquisition at both nuclei. In an in-vivo experiment, it was shown that without retuning the setup it was subsequently possible to obtain anatomical 1H images of a mouse under anesthesia with 19F images of a tiny tube filled with a fluorine-containing liquid and attached to the body of the mouse.
RESUMO
Metasurfaces are artificial electromagnetic boundaries or interfaces usually implemented as two-dimensional periodic structures with subwavelength periodicity and engineered properties of constituent unit cells. The electromagnetic bandgap (EBG) effect in metasurfaces prevents all surface modes from propagating in a certain frequency band. While metasurfaces provide a number of important applications in microwave antennas and antenna arrays, their features are also highly suitable for MRI applications. In this work we perform a proof-of-principle experiment to study finite structures based on mushroom-type EBG metasurfaces and employ them for suppression of inter-element coupling in dipole transceive array coils for body imaging at 7T. We firstly show experimentally that employment of mushroom structures leads to reduction of coupling between adjacent closely-spaced dipole antenna elements of a 7T transceive body array, which reduces scattering losses in neighboring channels. The studied setup consists of two active fractionated dipole antennas previously designed by the authors for body imaging at 7T. These are placed on top of a body-mimicking phantom and equipped with the manufactured finite-size periodic structure tuned to have EBG properties at the Larmor frequency of 298MHz. To improve the detection range of the B1+ field distribution of the top elements, four additional elements were positioned along the bottom side of the phantom. Bench measurements of a scattering matrix showed that coupling between the two top elements can be considerably reduced depending on the distance to the EBG structure. On the other hand, the measurements performed on a 7T MRI machine indicated redistribution of the B1+ field due to interaction between the dipoles with the structure. When the structure is located just over two closely spaced dipoles, one can reach a very high isolation improvement of -14dB accompanied by a strong field redistribution. In contrast, when put at a certain height over the antennas the structure provides a moderate isolation improvement together with a slight increase of B1+ level. This study provides a tool for the decoupling of dipole antennas in ultrahigh field transceive arrays, possibly resulting in denser element placement and/or larger subject-element spacing.
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It is revealed that the unique properties of ultrathin metasurface resonators can improve magnetic resonance imaging dramatically. A metasurface formed when an array of metallic wires is placed inside a scanner under the studied object and a substantial enhancement of the radio-frequency magnetic field is achieved by means of subwavelength manipulation with the metasurface, also allowing improved image resolution.