Effect of Ramadan on neutrophil's respiratory burst [innate immunity] and circulating immune complex

The aim of this study was to investigate the effects of Ramadan fasting on neutrophil's respiratory burst and circulating immune complex [CIC] level. The effects of Ramadan fasting on neutrophil's respiratory burst and CIC was studied in 21 normal young fasting Muslim individuals using standardized chemiluminescence and poly ethylene glycol methods respectively, the results obtained and statistically analysed. It was shown that in 11 cases out of 21 [52%] both of the chemiluminescence [CL] activity and CIC levels measured before and after Ramadan fasting were in normal range in spite of a insignificant decrease or increase in CL activity or CIC level. Therefore, the changes of the immunological parameters were not significant and the levels remained in the range of normal. In four cases out of 21 [24%], the CL activity and CIC levels were higher than normal range measured just before Ramadan, however after month of Ramadan the CL activity and CIC level decreased reaching to the normal level of these parameters. In four cases out of 21 [24%] there were an increase in CL activity and CIC levels after Ramadan fasting. There were no significant changes of CL activity of circulating neutrophils and CIC levels comparing the results obtained before and after Ramadan. More over there was a good correlation between these two immunological parameters measured in the present study

Circulating immune complex during Ramadan

Fasting during Ramadan represent one of the five pillars of the Islamic religion. So it is important to know the effect of this kind of fasting on people's life especially on their health. The purpose of this study was to show the effect of fasting during Ramadan on circulating immune complex [CIC] level and immune system. The CIC levels were measured before and after Ramadan by polyethylenglycole method. The blood samples were examined using quantitation chemiluminesence and circulating immune techniques. The results were analyzed using t-test and calculated coefficient correlation between CIC before and after Ramadan. There was no significant difference between the CIC level before and after Ramadan. According to the results, fasting during Ramadan does not have bad effect on immune system of healthy people