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Medicina (B.Aires) ; Medicina (B.Aires);67(2): 151-155, 2007. ilus
Article in Spanish | LILACS | ID: lil-480614

ABSTRACT

La paquimeningitis hipertrófica es una enfermedad poco frecuente caracterizada por engrosamiento de la duramadre. Presentamos una paciente con esta enfermedad que se manifestó con cefalea crónica y en la que concomitantemente se evidenció una glomerulonefritis necrotizante extracapilar pauciinmune asociada a anticuerpos anticitoplasma de neutrófilos de patrón perinuclear (ANCA-P). El diagnóstico se estableció por resonancia nuclear magnética. Recibió tratamiento inmunosupresor con prednisona y ciclofosfamida con evolución favorable.


Hypertrophic pachymeningitis is a very unusual disease, the main characteristic of which is thickening of the dura mater. We describe a patient who started this illness showing chronic headache and pauci-immune necrotizing extracapillary perinuclear antineutrophil cytoplasmic antibody (P-ANCA) associated glomerulonephritis. The diagnosis was made by brain magnetic resonance image. She received immunosuppressant therapy with prednisonel and cyclophosphamide with clinical improvement.


Subject(s)
Humans , Female , Adult , Antibodies, Antineutrophil Cytoplasmic/blood , Glomerulonephritis/etiology , Meningitis/etiology , Vasculitis/complications , Anti-Inflammatory Agents/therapeutic use , Cyclophosphamide , Glomerulonephritis/diagnosis , Glomerulonephritis/drug therapy , Headache/etiology , Immunosuppressive Agents/therapeutic use , Magnetic Resonance Imaging , Meningitis/diagnosis , Meningitis/drug therapy , Prednisolone/therapeutic use , Vasculitis/drug therapy , Vasculitis/immunology
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