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1.
Arch. latinoam. nutr ; 42(4): 395-402, dic. 1992. ilus, tab, graf
Article in English | LILACS | ID: lil-134589

ABSTRACT

Histological studies of the spleen and thymus of rats fed raw black beans (Phaseolus vulgaris) show an atrophy of both lymphoid organs. Decrease in relative thymus weight was most marked. All histological organization of this organ appeared altered. An evident decrease in cell number was also observed in both organs. Proliferative response of splenic cells stimulated in vitro with Concanavalin A was increased as compared to that from animals fed the control diet. It is likely that histological changes observed in the spleen and the thymus are due mainly to a protein caloric deficiency, although the possibility that toxic factors present in the raw diet have an effect on the immune system of the rat can not be overruled


Subject(s)
Animals , Male , Fabaceae , Food Handling , Immunologic Deficiency Syndromes/chemically induced , Lymphocyte Activation/drug effects , Spleen/drug effects , Thymus Gland/drug effects , Atrophy , Body Weight/drug effects , Dietary Proteins/pharmacokinetics , Dietary Proteins/toxicity , Enzyme Inhibitors/toxicity , Hot Temperature , Fabaceae/toxicity , Organ Size/drug effects , Phytohemagglutinins/toxicity , Plant Proteins/pharmacokinetics , Plant Proteins/toxicity , Rats , Rats, Sprague-Dawley , Spleen/pathology , Tannins/toxicity , Thymus Gland/pathology
2.
Arch. latinoam. nutr ; 35(1): 70-9, mar. 1985. tab
Article in Spanish | LILACS | ID: lil-27399

ABSTRACT

Se compara la composición de nutrientes y factores antinutricionales, así como la digestibilidad y crecimiento, en ratas alimentadas con dietas preparadas a base de las semillas de un cultivar negro de Ph. vulgaris, "Tacarigua", y un cultivar negro de Ph. lunatus, "Tapiramo". Los granos cocidos de ambos cultivares se distinguen muy poco en su aspecto, sabor, valor nutricional y aceptabilidad. Las semillas de Ph. vulgaris continen más proteínas y fósforo que las de Ph. lunatus. El puntaje "score" químico para lisina y la disponibilidad de este aminoácido fue mejor en el caso del Ph. lunatus. Las dietas elaboradas con semillas crudas de Ph. lunatus no demostraron ser tóxicas para las ratas luego de 12 días de administrárseles, contrariamente a lo observado con el Ph. vulgaris. Se observa una mejor eficiencia proteínica con las semillas cocidas de Ph. lunatus. Se recomienda la producción del cultivar "Tapiramo" (Ph. lunatus) para autoconsumo de los pequeños agricultores


Subject(s)
Rats , Animals , Male , Female , Fabaceae , Nutritive Value , Seeds/analysis , Plant Proteins, Dietary/pharmacology , Diet , Growth/drug effects , Lysine/analysis , Seeds/toxicity , Plant Proteins, Dietary/analysis
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