1.
Southeast Asian J Trop Med Public Health
; 1985 Sep; 16(3): 395-400
Article
in English
| IMSEAR
| ID: sea-30656
ABSTRACT
A study on the adverse reactions, occurring after treating microfilaremic patients infected with B. malayi, revealed that all reacted to a single oral dose of DEC (5 mg/kg). The major reactions were fever, headache, anorexia, abdominal pain, muscle and joint pains, nausea and vomiting. There seemed to be no association between the time of fever onset and microfilarial density, but the number of cases observed was too small to make any firm conclusion. There was a tendency for more severe reactions to occur in patients with higher microfilaria counts. Local reactions, probably due to destruction of adult worms, were seen in 3 patients. The reactions were serious enough to necessitate the patients spending approximately 48 hours in bed.
Subject(s)
Adolescent , Adult , Blood Pressure/drug effects , Brugia , Child , Diethylcarbamazine/administration & dosage , Elephantiasis, Filarial/drug therapy , Female , Fever/chemically induced , Humans , Indonesia , Lymphedema/drug therapy , Male , Middle Aged
2.
Article
in English
| IMSEAR
| ID: sea-22182