ABSTRACT
Abstract Objective The present article presents a literature review concerning the microbiota of breast milk and the influence of epigenetics in the susceptibility to COVID-19. Methods A literature review. Results Breastfeeding transfers microbiota, nutrients, diverse white blood cells, prebiotics, hormones, and antibodies to the baby, which provide short- and longterm immunological protection against several infectious, gastrointestinal, and respiratory illnesses. The little evidence available shows that breast milk very rarely carries the SARS-CoV-2 virus, and even in those cases, it has been discarded as the source of contagion. Conclusion The reviewed studies show evidence of a beneficial effect of breastfeeding and highlights its importance on the current pandemic due to the immune reinforcement that it provides. Breastfed individuals showed better clinical response due to the influence on the microbiota and to the nutritional and immune contribution provided by breast milk, compared with those who were not breastfed.
Resumo Objetivo O presente artigo apresenta uma revisão de literatura sobre amicrobiota do leite materno e a influência da epigenética na suscetibilidade à COVID-19. Métodos Revisão de literatura. Resultados A amamentação transfere microbiota, nutrientes, diversos glóbulos brancos, prebióticos, hormônios e anticorpos para o bebê, os quais proporcionam proteção imunológica de curto e longo prazo contra diversas doenças infecciosas, gastrointestinais e respiratórias. As poucas evidências disponíveis mostram que o leite materno transportamuito raramente o vírus SARS-CoV-2, emesmo nestes casos, ele foi descartado como fonte de contágio. Conclusão Os estudos revisados mostram evidências de um efeito benéfico da amamentação e destacam sua importância na atual pandemia devido ao reforço imunológico que ela proporciona. Os indivíduos amamentados mostraram melhor resposta clínica devido à influência sobre a microbiota, e à contribuição nutricional e imunológica proporcionada pelo leite materno, em comparação com aqueles que não o foram.
Subject(s)
Humans , Infant, Newborn , Microbiota , SARS-CoV-2 , COVID-19 , Milk, HumanABSTRACT
Propósito dela revisión:El objetivo de la revisión es delinear el rol de la Lactancia materna en mujeres con sospecha o diagnóstico de COVID-19. Buscamos reportes en donde se incluye el rol de la microbiota de la leche materna bajo las condiciones de la pandemia de COVID-19. Recientes Hallazgos: Actualmente existen reportes de detección de anticuerpos contra SARS-CoV en la sangre del cordón umbilical y en la leche materna.La placenta tiene una expresión muy baja de los receptores de la enzima convertidora de angiotensina (ECA2) que parecen limitar la entrada de SARS-CoV-2al feto. Extracto: El apego precoz del recién nacido a su madre y la lactancia materna en la primera hora después del nacimiento, al igual que el mantenimientode la lactancia exclusiva en los primeros 6 meses de vida, garantizan un crecimiento y desarrollo adecuados, así como la protección inmunológica a enfermedades, especialmente respiratorias y digestivas. En el caso de madres con COVID-19, no se ha documentado transmisión vertical de la madre al hijo. No hay evidencia del virus en el líquido amniótico al momento del nacimiento de un bebé ni en la leche materna, por lo que se indica continuar la lactancia, pero cumpliendo rigurosamente las medidas de seguridad e higiene. Adicionalmente, se ha reportado que el tipo de parto y el manejo del mismo podrían estar implicados en el contagio por COVID-19, a través de sangre, heces fecales y otros.
Purpose of the review: The objective of the review is to delineate the role of Breastfeeding in women with suspected or diagnosed COVID-19. We are looking for reports that include the role of the breast milk microbiota under the conditions of the COVID-19 pandemic. Recent Findings: Currently there arereports of detection of antibodies against SARS-CoV in umbilical cord blood and breast milk. The placenta has a very low expression of angiotensin-converting enzyme (ACE2) receptors that appear to limit the entry of SARS-CoV-2 into the fetus. Extract: Theprecocious attachment of the newborn to its mother and breastfeeding in the first hour after birth, as well as the maintenance of exclusive breastfeeding in the first 6 months of life, guarantee adequate growth and development, as well as the immunological protection against diseases, especially respiratory and digestive. In the case of mothers with COVID-19, vertical transmission from mother to child has not been documented. There is no evidence of the virus in the amniotic fluid at the time of the birth of a baby or in breast milk, so it is indicated to continue breastfeeding, but strictly complying with safety and hygiene measures. Additionally, it has been reported that the type of delivery and its management could be involved in the spread of COVID-19,through blood, feces and others