ABSTRACT
Objective To compare and analyze the risk factors of cerebral insufficiency, and to explore the application of thermal texture maps (TTM) in the diagnosis and screening of cerebral insufficiency. Methods 8787 healthy subjects were selected as the research object, and theit clinical data were collected, including blood pressure, blood lipid, X-ray of cervical vertebra, Doppler ultrasound of the stiff artery, cranial magnetic resonance imaging (MRI) and TTM examination. Subjects were grouped according to the results of TTM examination of cerebral insufficiency, and high risk factors for cerebral insufficiency were comparatively analyzed. The results of TTM and MRI in diagnosis of cerebral ischemia were comparative analysis. Results Among the 8787 subjects, 3734 subjects (42.49％) had cerebral insufficiency (TTM positive group), and 5053 (57.51％) had no significant abnormalities (TTM negative group). The differences between the two groups in high risk factors were statistically significant, including obesity, abnormal low density lipoprotein cholesterol, smoking, alcoholism, hypertension, multiple cerebral ischemia and carotid atherosclerosis (all P<0.01). By taking the MRI as the gold standard, the sensitivity, specificity, positive and negative predictive value of brain blood supply TTM for diagnosing focal cerebral ischemia was 84.63％, 65.17％, 30.66％ and 95.88％, respectively. Conclusions TTM can be an important early warning index of cerebral insufficiency in disease despreventive and intervention.