ABSTRACT
PURPOSE: To determine the effects of massage therapy on growth, development, hormones, immune function, hepatic function, hematopoietic function and sleep pattern of preterm infants. METHODS: Thirty-one preterm infants of less than 35 weeks gestational age, who were admitted to Eulji Medical College Hospital Neonatal Intensive Care Unit between August 1998 and May 1999, and were in the state without mechanical ventilation or oxygen therapy, and hemodynamically stable with no acute disease state non congenital anomaly, and who were also fed by oral route or gastric tube, were enrolled in this study. The randomly selected massage group(15 neonates) received three 15-minute periods of tactile and kinesthetic stimulation daily for 7 days, and the control group(16 neonates) received general nursing care. We measured gastrin, thyroid function test, serum cortisol, CH50, IgG, IgM, CBC and liver function test in both groups before and after the study. During observation for 7 days, neonate behaviors were recorded every hour for 10sec using the analysis of 6 sleep-wake states. RESULTS: Although the massage group showed slight differences in blood level of Thyroid stimulating hormone, CH50, hemoglobin, hematocrit and body weight and alertness as compared with control group, there was no statistically significant difference between the two groups. CONCLUSION: Several positive effects of massage on the preterm infants that have been reported previously must be reevaluated.
Subject(s)
Humans , Infant, Newborn , Acute Disease , Body Weight , Gastrins , Gestational Age , Hematocrit , Hydrocortisone , Immunoglobulin G , Immunoglobulin M , Infant, Premature , Intensive Care, Neonatal , Liver Function Tests , Massage , Nursing Care , Oxygen , Respiration, Artificial , Thyroid Function Tests , ThyrotropinABSTRACT
We experienced a case of primary hepatic actinomycosis which was initially diagnosed by means of fine needle aspiration. The patient was a 31-year-old emaciated man with a 2-month history of 10 kg weight loss, right upper quadrant pain and flank pain. The liver was palpable and tender on physical examination. Computerized tomography scan of the liver showed two ill-defined hypodense masses in gallbladder fossa and inferior pole of right lobe. Hepatocellular carcinoma was clinically suspected. A CT-guided fine needle aspiration was performed. Microscopically, smears showed numerous radiating clusters of filamentous bacteria with many neutrophils and monocytes in necrotic background. The symptoms were improved by incision and drainage and massive administration of penicillin.
Subject(s)
Adult , Humans , Actinomycosis , Bacteria , Biopsy, Fine-Needle , Breast , Carcinoma, Hepatocellular , Diverticulum , Drainage , Fibroadenoma , Flank Pain , Gallbladder , Infarction , Liver , Monocytes , Neutrophils , Penicillins , Physical Examination , Vesico-Ureteral Reflux , Weight LossABSTRACT
Hydrocephalus is a common malformation of the central nervous system and its cause may be either congenital or acquired. The imbalance between CSF formation and absorption, obstruction of CSF pathways, impaired venous absorption, and over secretion of CSF results in excessive accumulation of the fluid in the ventricles, leading to hydrocephalus. Although ventriculo-peritoneal shunt is regarded as the main and definitive therapy for rapidly progressive hydrocephalus, shunts in newborns have a high failure rate and thus there have been a search for alternative non-invasive techniques. Acetazolamide is a carbonic anhy- drase inhibitor, which acts by reducing production of CSF in the choroid plexus. Admini- stration of acetazolamide will decrease the rate of CSF production, preventing progressive ventricular enlargement. We experienced three cases of neonatal hydrocephalus successfully treated by long-term administration of acetazolamide. Brief review and related literatures were also presented.
Subject(s)
Humans , Infant, Newborn , Absorption , Acetazolamide , Carbon , Central Nervous System , Choroid Plexus , Hydrocephalus , Ventriculoperitoneal ShuntABSTRACT
Maple syrup urine disease (MSUD) is an autosomal recessive disease caused by a deficiency in subunits of the branched-chain alpha-ketoacid dehydrogenase complex (BCKDH). The disease is characterized by the accumulation of the branched-chain amino acids leucine, isoleucine, valine, alloisoleucine, and their corresponding alpha-ketoacid in blood and urine. MSUD is a heterogenous disorder, and classic, intermittent, intermediate and thiamine-responsive phenotypes have been identified. We experienced a case of Maple syrup urine disease (classic type) in a female neonate, who suffered from lethargy, poor feeding, apnea, alternating periods of hypertonicity and flaccidity, generalized convulsions, and a peculiar burned sugar smell from the body and urine. She died of respiratory failure 22 days after the birth. The brief review of the literature was made.
Subject(s)
Female , Humans , Infant, Newborn , Acer , Amino Acids, Branched-Chain , Apnea , Burns , Isoleucine , Lethargy , Leucine , Maple Syrup Urine Disease , Oxidoreductases , Parturition , Phenotype , Respiratory Insufficiency , Seizures , Smell , ValineABSTRACT
No abstract available.
Subject(s)
Humans , Infant, Newborn , Body Weight , Infant, Low Birth WeightABSTRACT
No abstract available.
Subject(s)
Humans , Infant , Infant, Newborn , Infant, Low Birth Weight , Parathyroid HormoneABSTRACT
No abstract available.
ABSTRACT
No abstract available.