Topical Oxygen Jet Therapy (TOJT) for treating infected chronic surgical wounds

ABSTRACT Objectives: To evaluate the effectiveness of Topical Oxygen Jet Therapy (TOJT) in the treatment of surgical wounds in adult patients who has clinical signs of infection for over 30 days; and to identify the pathogens causing complicated skin and soft tissue infections. Method: Parallel, randomized clinical trials randomly divided into "Control Group" (CG) and "Treatment Group" (TG), which were followed up for 10 consecutive days. Venous antibiotics and dressings were used in both groups. In addition, TOJT were used on the wounds in the TG. The outcome criteria were based on clinical indicators: Pressure Ulcer Scale for Healing (PUSH) and Visual Analog Scale Pain (VAS). The paired t-test or Wilcoxon, chi-squared or Fisher's exact test, and Student's t-test or Mann-Whitney tests were used with a significance level of 5%. Results: 73 inpatients were included and followed up: 39 in TG and 34, CG. There were no significant differences in socio-demographic variables or of initial laboratory tests, except for blood glucose that was higher in TG than in CG (p = 0.044). Ten days into treatment, both the area of PUSH wounds (p < 0.001) and the pain scale (p = 0.029) were significantly reduced in TG. Staphylococcus aureus was the most prevalent pathogen (40%) with no significant difference between the two groups. Discussion: Although the follow-up time was of only ten days, a significant improvement was observed in TG. As a limitation of the study, the small sample size precluded the comparison of S. aureus infections between the two groups. Conclusion: TOJT accelerated the healing process, reduced pain and contributed to an improvement in the clinical status of the wounds when compared to CG. These findings demonstrate the effectiveness and relevance of the employed technique. It can be easily incorporated as a routine procedure in hospitals without extra investment.

Doenças sexualmente transmissíveis e a vulnerabilidade da população do Alto Solimões, Amazonas, Brasil / Sexually transmitted diseases and the vulnerability of the population in the Alto Solimões region, in Amazonas, Brazil

Resumo Pessoas que apresentam sintomas de doenças sexualmente transmissíveis na região do Alto Solimões (Amazonas, Brasil), podem procurar farmácias mais próximas de onde residem para tratamento. Este artigo tem por finalidade mostrar como são tratadas e orientadas as pessoas que procuram pelo atendimento em farmácias em vez buscar os serviços de saúde, que são de mais difícil acesso na região. Para tal, realizou-se uma pesquisa de caráter qualitativo e emprego de uma amostra de conveniência. Na pesquisa de campo realizada em três dos nove municípios da região, utilizou-se o "Método do Cliente Misterioso" validado pelo protocolo Situational Analysis of Sexual Health in India (Sashi), desenvolvido pelo London School of Hygiene and Tropical Medicine, já utilizado na Índia, África e no Alto Solimões, seguido de entrevistas semiestruturadas com os mesmos participantes da etapa do cliente misterioso. Observou-se que, quando do uso do Método do Cliente Misterioso, os entrevistados indicaram e venderam antibióticos sem receita médica aos que os procuraram e, quando do uso das entrevistas semiestruturadas, essa prática não foi observada. Em ambas as abordagens, não houve orientação aos clientes sobre os riscos das doenças sexualmente transmissíveis para eles e seus parceiros sexuais. Concluímos com esse estudo que as pessoas que vivem no Alto Solimões estão vulneráveis a essas doenças, sendo necessário que se repense a questão da assistência médica e farmacêutica no âmbito das doenças sexualmente transmissíveis em regiões de difícil acesso do país.

Abstract People who present symptoms of sexually transmitted diseases in the Alto Solimões region (Amazonas, Brazil) can seek treatment at the pharmacies nearest to their homes. This article has the purpose of showing how people who seek assistance in pharmacies, instead of in the health care services, which are less accessible in the region, are treated and oriented. For this, we made a research of qualitative nature and used a convenience sample. Field research was performed in three of the nine municipalities of the region. The "Mystery Client Method" validated by the Situational Analysis of Sexual Health in India (Sashi) Protocol developed by the London School of Hygiene and Tropical Medicine, already used in India, Africa, and in the Alto Solimões region, was used, followed by semi-structured interviews with the same participants of the mystery client phase. It was observed that, when using the Mystery Client Method, the respondents indicated and sold antibiotics without doctor's prescriptions to those who sought it, and when using the semi-structured interviews, this practice was not found. In both approaches, there was no orientation to the clients on the risks of the STDs for themselves and their sexual partners. With this study, we conclude that people living in the Alto Solimões region are vulnerable to such diseases, and it is necessary to rethink the issue of the medical and pharmaceutical assistance in the context of the sexually transmitted diseases in regions of difficult access in the country.