Subject(s)
Humans , Male , Adenomatous Polyposis Coli/pathology , Colon/pathology , Rectum/pathologyABSTRACT
Nevus lipomatosus cutaneous superficialis [NLCS] of Hoffmann-Zurhelle is a rare hamartomatous skin lesion histologically characterised by the presence of mature fat tissue within the dermis. Clinically, two types of NLCS are distinguished: a multiple type and a solitary type. Illustration of anatomoclinical presentation of this rare lesion and the hypothesis of its pathogenesis. We report a case of a NLCS diagnosed in a 16-year-old girl, which was exceptional by its huge volume. This lesion was localised in the right thigh. The patient underwent wide excision of the mass without complication. The tumoral form is rarely reported in the literature, and its pathogenesis is unknown
Subject(s)
Humans , Female , Skin Neoplasms , Lipomatosis , Hamartoma , Skin , ThighABSTRACT
Clear cell sarcoma [or malignant melanoma] of soft parts is a rare malignancy that is found in the young adults and is generally located in the extremities of the limbs. In this study, we report a new case diagnosed in a 23-year old male revealed by a slowly enlarging mass of the knee. The histopathologic pattern of the mass was composed of nests and stands of fusiform or round cells alternating with bands of sclerotic stroma. The tumoral cells presented abundant, eosinophilic and sometimes clear cytoplasm. Some cells contain brown pigment which is Fontana [+]. Vimentin, S100 protein and HMbeta45 antibodies were expressed by the tumoral cells confirming the diagnosis of soft tissue clear cell sarcoma. Large surgical resection was performed with no recurrence eight months after