ABSTRACT
Objective:To investigate the effect of Bailing capsule combined with budesonide on inflammatory factors and quality of life in patients with chronic obstructive pulmonary disease (COPD).Methods:From January 2017 to December 2018, 86 cases admitted to Luqiao Hospital of Taizhou Enze Medical Center were divided into observation group (43 cases) and control group (43 cases) according to the random table method.The patients in the control group were treated with budesonide and formoterol, while the patients in the observation group were treated with Bailing capsule on the basis of the control group.The course of treatment in both two groups was 3 months.The therapeutic effect, lung function, inflammatory factors, quality of life and adverse reactions were compared before and after treatment.Results:The effective rate of the observation group (93.02%) was higher than that of the control group (72.09%) (χ 2=6.541, P<0.05). After treatment, the FEV 1[(1.69±0.15)L], FEV 1%[(64.29±2.69)%] and FVC[(2.69±0.16)L] in the observation group were higher than those in the control group[(1.48±0.18)L, (57.83±2.30)% and (2.41±0.18)L]( t=5.877, 11.969, 7.624, all P<0.05). The levels of TNF-α[(17.35±2.80)ng/L], IL-6[(18.91±2.24)ng/L] and IL-8[(12.01±1.73)ng/L] in the observation group were lower than those in the control group[(25.26±2.31)ng/L, (24.65±3.27)ng/L and (15.45±1.50)ng/L]( t=14.290, 9.496, 9.852, all P<0.05). The CAT score of the observation group[(11.72±1.92)points] was lower than that of the control group[(15.41±2.24)points]( t=8.202, P<0.05). No significant adverse reactions occurred in both two groups. Conclusion:Bailing capsule combined with budesonide in the treatment of COPD is effective, it can reduce the inflammatory reaction, improve the pulmonary function and quality of life, and has no obvious adverse reactions, with good safety.