ABSTRACT
Abstract INTRODUCTION: Infective endocarditis (IE) is a systemic infectious disease requiring a multidisciplinary team for treatment. This study presents the epidemiological and clinical data of 73 cases of IE in Rio de Janeiro, Brazil. METHODS This observational prospective cohort study of endocarditis patients during an eight-year study period described 73 episodes of IE in 70 patients (three had IE twice). Community-associated (CAIE) and healthcare-acquired infective endocarditis (HAIE) were diagnosed according to the modified Duke criteria. The collected data included demographic, epidemiologic, and clinical characteristics, including results of blood cultures, echocardiographic findings, surgical interventions, and outcome. RESULTS: Analysis of data from the eight-year study period and 73 cases (70 patients) of IE showed a mean age of 46 years (SD=2.5 years; 1-84 years) and that 65.7% were male patients. The prevalence of CAIE and HAIE was 32.9% and 67.1%, respectively. Staphylococcus aureus (30.1%), Enterococcus spp. (19.1%), and Streptococcus spp. (15.0%) were the prevalent microorganisms. The relevant signals and symptoms were fever (97.2%; mean 38.6 + 0.05°C) and heart murmur (87.6%). Vegetations were observed in the mitral (41.1%) and aortic (27.4%) valves. The mortality rate of the cases was 47.9%. CONCLUSIONS: In multivariate analysis, chronic renal failure (relative risk [RR]= 1.60; 95% confidence interval [CI] 1.01-2.55), septic shock (RR= 2.19; 95% CI 1.499-3.22), and age over 60 years (RR= 2.28; 95% CI 1.44-3.59) were indirectly associated with in-hospital mortality. The best prognosis was related to the performance of cardiovascular surgery (hazard ratio [HR]= 0.51; 95% CI 0.26-0.99).
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Aged , Aged, 80 and over , Young Adult , Endocarditis, Bacterial/epidemiology , Staphylococcal Infections , Staphylococcus aureus/isolation & purification , Brazil/epidemiology , Prospective Studies , Hospital Mortality , Endocarditis, Bacterial/diagnosis , Endocarditis, Bacterial/microbiology , Tertiary Care Centers , Middle AgedABSTRACT
Neste artigo apresentamos um caso de tumor fibroso solitário da pleura, em um homem de 49 anos, cujo diagnóstico foi feito em nosso hospital, anos após o surgimento dos primeiros sintomas e sinais na radiografia do tórax. Após descrição do caso, fizemos uma breve revisão sobre aspectos mais importantes deste raro tumor, visando auxiliar no diagnóstico diferencial das neoplasias torácicas.
Subject(s)
Humans , Male , Adult , Pleural Neoplasms/diagnosis , Solitary Fibrous Tumor, Pleural/diagnosis , Diagnostic Imaging , Signs and SymptomsABSTRACT
Introdução: O usuo de levosimendan em pacientes criticamente enfermos e, principalmente, nos que se apresentam com pressão arterial média inferior a 60mmHG, ainda não teve a sua eficácia e a sua segurança estabelecidas.Objetivos: avaliar a resposta do levosimendan em cardiopatas graves já em uso de dobutamina e noradrenalina.Métodos: foram avaliados de forma propspectiva 37 pacientes internados em ambiente de terapia intensiva geral e cardiológica, sendo 51,3 por cento (n=19) do sexo masculino e 48,7 por cento (n=18) do sexo feminino. A média de idade doi de 65,3 anos, variando entre 49 e 84 anos, todos em classe funcional IV, segundo a classificação da NYHA, e dependentes da infusão venosa contínua de dobutamina com doses Superiores a 5ug/kg/min, sendo que 15 deles (40,5 por cento) estavam dependentes também de noradrenalina (dose acima de 0,05ug/kg/min)...