Importancia de las neurotrofinas en medicina humana veterinaria / Importance of neurotrophins in human medicine veterinary

Las neurotrofinas (NTs) son factores de crecimiento que ejercen la totalidad o parte de sus funciones sobreel sistema nervioso central y periférico. Las neurotrofinas son una familia de péptidos con propiedades neurotróficas y neurotrópicas que incluyen los siguientes compuestos: factor de crecimiento nerviosos, (nerve growth factor, NGF), factor de crecimiento derivado del cerebro (Brain-derived neurotrophic factor, BDNF), y las neurotrofinas 3 (NT-3), 4/5 (NT/4/5), (NT-6). Se trata de un conjunto de péptidos relacionados estructural yfuncionalmente, que favorecen la supervivencia y diferenciación fenotípica de su-poblaciones neuronales del sistemanervioso periférico durante el desarrollo embrionario y su mantenimiento durante la vida adulta. Además actúansobre algunos tipos de neuronas del sistema nervioso central. Por otro lado, estudios llevados a cabo en los últimosaños sugieren que las neurotrofinas podrían controlar algunas funciones en tejidos no nerviosos, especialmente enlos órganos linfoides y en las células inmunocompetentes. En medicina Humana se hadeterminado que en el aparato de la visión la falta de BDNF lleva: 1) a la pérdida de las células ganglionares de laretina y también es responsable del glaucoma en el hombre; 2) En el Sistema nervios causa depresión, epilepsia, enla enfermedad de Huntington; .3) y en la parte metabólica causa la diabetes tipo. Está comprobado que las dosprimeras (NTs) están presentes en el carcinoma de colon, páncreas y glándulas prostáticas, para estas dos patologíasya están en venta la anti-neurotrofinas que neutralizan a los NGF, BDNF, NT-3, NT 4/5NT e incluyen anticuerposgenerados así como sus fragmentos.En Medicina veterinaria se han detectados a los receptores de alta afinidad(Proteínas Trks) en el timo de todos los vertebrados inferiores y superiores. También en los órganos linfáticossecundarios de Sus scrofa domesticus y Lama glama; en el aparato digestivo y reproductor de Rattus norvergicus.

Neurotrophins (NTs ) are growth factors that exert all or part of its functions onthe central and peripheral nervous system. Neurotrophins are a family of peptides with neurotrophic and neurotropic properties include the following compounds: nerve growth factor ( nerve growth factor , NGF) , growth factor , brain derived ( Brain- derived neurotrophic factor , BDNF) , and neurotrophin 3 (NT -3 ) , 4 /5 ( NT/4/5 ) , ( NT - 6) . This is a set of structural and related peptides functionally , favoring survival and phenotypic differentiation of neuronal populations system su-peripheral nervous during embryonic development and maintenance during adulthood . Besides actingon some types of neurons of the central nervous system . Moreover, studies conducted in recentyears suggest that neurotrophins may control some functions in non-nervous tissues, especially inand lymphoid organs in immunocompetent cells . In Human medicine has determined that in the apparatus of the absence of BDNF vision leads : 1) a loss of ganglion cellsretina and is also responsible for glaucoma in man; 2) In the nerve system causes depression, epilepsy,Huntington 's disease ; 3 ) and in metabolic diabetes causes type part . It is proved that the twofirst (NTs ) are present in the carcinoma of the colon, pancreas and prostate glands , for these two pathologies Information already in the anti - neurotrophins that neutralize NGF , BDNF , NT -3 , NT and include antibodies 4/5NTgenerated and their fragmentos.En Veterinary Medicine detected to have high affinity receptors (Proteins Trks ) in the thymus of all lower and higher vertebrates. Also in the lymphatic organsHis side scrofa domesticus and Lama glama ; in the digestive tract and Rattus norvegicus.

Breve descripción de Taxorchis schistocotyle Beddard, 1914 (Trematoda, cladorchiidae) por microscopia electrónica de barrido / Short description of Taxorchis schistocotyle Beddard, 1914 (Trematoda, cladorchiidae) with scanning electron microscope

The study describes some morphological trait of Taxorchis schistocotyle Beddard, 1914 (Trematoda, Cladorcniidae) using scanning electron microscope (SEM). Specimens were removed from small instestine during necropsy of Hydrochoeris hydrochaeris (Rodentia, Hydrocheoridae). Samples were fixed in glutaraldehid 3 percent in sodium monoacid phosphate buffer with dehidratation in acetones of increasing graduation. Diagnosis technique used was useful to survey and differentiation among species that parasite Argentinean wild mammalians.

Infección por coccidios en carnívoros silvestres de cautiverio de Argentina / Coccidian infection in captive wild carnivores from Argentina

With the objective to determine the infection frequency by coccidia protozoa, 159 fecal samples from captive wiid camivores were analyzed. A 10.7 percent of the animal analyzed were positive to the infection. Whereas the family Procyonidae has a high percentage of positivity (35 percent), Canidae have lower infection ratio (23-33 percent) and Felidae only 0.3 percent). Family Musteldiae show negative findings

Frecuencia de infección por diphyllobothrium sp cestoda diphyllobothriidae en carnívoros silvestres de Argentina / Diphyllobothrium sp cestoda diphyllobothriidae infection frequency in Argentina wild carnivores

With the aims to determine the infection frequency by tapeworms of Diphyllobothrium genus 30 samples from captive wild carnivores were analyzed. A 30 percent of the animal analyzed was positive to the infection. Whereas the family Procionidae has a high percentage of positivity (60 percent). Canidae have lower infection ratio (20-25 percent). The accuracy for the diagnosis of Diphylobothrium was made by the morphology of scolex, proglottids and eggs. This is the first report of the parasite presence in Argentine wild carnivores

The lymphatic system of the anterior limb in Dasypus novemcinctus novemcinctus Linne, 1758 (mammalia:Edentata)

Revisäo a respeito da drenagem linfática do membro anterior em Dasypus novemcinctus novemcinctus. Foram utilizados 15 tatus, clinicamente säos, de ambos os sexos, capturados no Nordeste e injetados segundo o método da "Pasta de Gerota Modificada". A punçäo foi realizada no quarto dedo tanto medial quanto lateralmente, na zona interfalangiana e de ambos os lados da glândula mamária peitoral esquerda. As dissecaçöes clássicas foram realizadas utilizando-se microscópio de cirurgia tipo Varimes. As fotomicrografias foram tomadas com auxílio de microscópio tipo Zeiss. A análise exaustiva da regiäo do membro torácico levou-nos às seguintes conclusöes: o percurso linfático se efetuava desde a extremidade distal da regiäo injetada até o linfonodo axilar, deste partindo 2 a 3 vasos linfáticos eferentes que se projetavam no linfonodo inguinofemoral superficial. O linfonodo situado junto à borda caudal da escápula (descrito pela primeira vez) recebia vaso linfático eferente do linfonodo cervical superficial e outro vaso linfático eferente que se projetava em direçäo ao linfonodo axilar