ABSTRACT
Adenoid cystic carcinoma, an uncommon malignant salivary gland neoplasm, is known for its long clinical course, indolent growth, local recurrence and late distant metastasis. We report an unusual case of adenoid cystic carcinoma of the palate in a 64-year-old woman, undiagnosed for more than 15 years, who presented as malignant pleural effusion.
Subject(s)
Carcinoma, Adenoid Cystic/diagnosis , Carcinoma, Adenoid Cystic/pathology , Carcinoma, Adenoid Cystic/secondary , Female , Humans , Middle Aged , Palatal Neoplasms/diagnosis , Palatal Neoplasms/pathology , Pleural Effusion, Malignant/etiology , Pleural Neoplasms/pathology , Pleural Neoplasms/diagnostic imaging , Pleural Neoplasms/secondaryABSTRACT
A 30 year-old housewife presented with cough and shortness of breath which progressed during her ensuing pregnancy, culminating in a still-birth at 9 months of gestation and requiring her hospitalisation in the immediate postpartum period. HRCT scan of the thorax showed thin-walled cysts and open lung biopsy confirmed the clinical impression of lymphangioleiomyomatosis. She was put on oral medroxyprogesterone acetate. After disease flare-up in the postpartum period her symptoms have stabilised.
Subject(s)
Adult , Antineoplastic Agents, Hormonal/therapeutic use , Female , Humans , Lymphangioleiomyomatosis/diagnosis , Medroxyprogesterone Acetate/therapeutic use , Pregnancy , Pregnancy Complications/diagnosisABSTRACT
The carrier rate of Group A Streptococcus (GAS) was studied amongst 932 children from 1+ upto 12 years of age in three major racial groups in the foothills of the Darjeeling district of West Bengal. It was altogether 13 per cent and was found to be evenly distributed in the three ethnic groups as Gurkhas: 11 per cent, Rajbanshis: 15 per cent and Cosmopolitans: 13 per cent, but the incidence of Rheumatic fever and/or Rheumatic heart diseases were unnoticed among the Gurkha children who also had significant low ASO titres.
Subject(s)
Carrier State/ethnology , Chi-Square Distribution , Child , Child, Preschool , Female , Humans , India/epidemiology , Infant , Latex Fixation Tests , Male , Prospective Studies , Streptococcal Infections/ethnology , Streptococcus pyogenes/isolation & purificationABSTRACT
Susceptibility and/or immune response to tuberculosis may or may not be associated with particular histocompatibility leucocyte antigen (HLA) phenotype frequencies. The present study was undertaken to north eastern Indian population to verify any association between HLA phenotypes and immune response to mycobacterial antigen. HLA-typing was done in 60 well Tarasaki trays and T-cell subsets in each group were measured using Ficoll-hypaque nylon wool columns and dynabeads (M-450). No universal association with particular HLA-type and pulmonary tuberculosis has been confirmed.
Subject(s)
Adolescent , Adult , Case-Control Studies , Disease Susceptibility , Female , Gene Frequency , HLA Antigens/genetics , Histocompatibility Testing , Humans , India , Male , Phenotype , Tuberculosis, Pulmonary/geneticsABSTRACT
The study comprising smoking habits among educationally and socially forward class, its impact on respiratory system and response of the said class of people to a questionnaire was undertaken among a random sample of 1188 subjects consisting of students and professionals aged between 15 and 65 years. Results showed that smoking habit was alarmingly high (48.8%) among the students and a little higher (53%) among the professionals. The exact nature and extent of the problem of smoking was not very much clear to all the subjects.