ABSTRACT
Introduction: Hypogonadism in aging male is defined as [Syndrome caused by androgen deficiency which affect multiple organ functions and qualityof life]. Patients present with different symptoms like male erectile dysfunction, decreased sexual desire, anemia etc.
Objectives: To demonstrate the serum testosterone levels and prevalence of hypogonadism in different age groups and their correlation with symptoms of hypogonadism
Study Design: Cross sectional comparative study
Settings: Allied Hospital Faisalabad. Duration: 3 years and 6 months, from Dec 1, 2015 to May 30, 2018
Methodology: 180 healthy looking males were randomly taken from attendants of patients of Urology Department from indoor or from OPD and categorized into six groups according to their age decades: starting from Group-I [20-29 years] and ending at Group 6 [70 years and above]. Informed consent was taken. Symptoms of every person were recorded on Aging male symptoms scale [AMS]proforma/questionnaire. BMI, testicular volume,serum testosterone, Albumin, estradiol, SHBG, HbA1c and Blood Sugar were recorded. Results were recorded and put in SPSS version 10 for statistical analysis
Results: Average serum testosterone of different groups was 9.43+/-2.7ng/ml. The study shows a decrease in average serum testosterone level by 28.95 percent with advancing age. This difference is statistically not significant [chi square test, p-value 0.554]. The prevalence of hypogonadism was 10 percent in advanced age groups of our study population and all persons having low testosterone were symptomatic. Study showed93.44percentincrease in the severity of symptoms with advancing age
Conclusion: Serum testosterone falls with advancing age leading to differentsymptoms of hypogonadism but it is under reported as none of the persons was aware of this problem