ABSTRACT
Objective To design an auxiliary measurement device for anterior cruciate ligament injury in order to improve the accuracy of specialist examination and postoperative functional assessment.Methods The device consisted of a main frame and support pads,which was designed based on the principles of anatomopathology and mechanical mechanics.The frame was set above and paralleled to the tibia,and the measurement scale was put at the vertical direction of the frame.The support pads were fixed to the tibia and patella respectively to execute auxiliary measurement by providing opposite acting force.Results The success rate of preliminary diagnosis by the device was higher than that by traditional method.Conclusion The device gains advantages in convenience,practicality,low cost and etc,and is worthy promoting in the orthopedics department.
ABSTRACT
<p><b>OBJECTIVE</b>The purpose of this study was to investigate the relationship between IL-1 gene polymorphisms and susceptibility to severe periodonitis in Chinese of the Han Nationality.</p><p><b>METHODS</b>DNA samples with buccal swabs were collected from 30 patients with severe adult periodontitis (AP), 20 patients with rapid progressive periodontitis (RPP) and 94 healthy control (HC) individuals. Polymorphisms in the IL-1 gene cluster were analyzed with PCR-RFLP.</p><p><b>RESULTS</b>It was found that the frequency of IL-1B + 3953/Taq I allele 2 was significantly higher in severe AP patients (OR = 6.8, P < 0.05) and RPP patients (OR = 9.6, P < 0.05) than in healthy controls, and the frequency of IL-1RN intron II/VNTR allele 2 was significantly higher in the group of severe AP patients (OR = 6.3, P < 0.05) than in the group of healthy controls.</p><p><b>CONCLUSION</b>IL-1B + 3953/Taq I allele 2 and IL-1RN nitrol IL/VNTR allele 2 are genetic indicators of susceptibility to severe AP and RPP, and both AP and RPP are genetic heterogeneous.</p>