Comparison of the effects of horizontal and vertical micro-osteoperforations on the biological response and tooth movement in rabbits / 대한치과교정학회지

Objective@#This study aimed to compare the amount of tooth movement after multiple horizontal (MH) and single vertical (SV) micro-osteoperforations (MOPs), and evaluate the histological changes after orthodontic force application in rabbits. @*Methods@#The mandibles of 24 white rabbits were subjected to two experimental interventions: MH and SV MOPs. Defect volume of the MOPs between the two groups was kept similar. A force of 100 cN was applied via a coil spring between the incisor teeth and the first premolars. The amount of tooth movement was measured. Differences in the amount of tooth movement and bone variables at three time points and between the two groups were evaluated using repeated-measures analysis of variance. @*Results@#The first premolar showed a mesial movement of 1.47 mm in the MH group and 1.84 mm in the SV group, which was significantly different at Week 3 (p < 0.05). No significant difference was observed in bone volume and bone fraction between the groups. Tartrate-resistant acidic phosphatase-positive cell count was also significantly greater at Week 3 than at Week 1 in both the SV and MH groups. @*Conclusions@#The amount of tooth movement showed significant differences between Weeks 1 and 3 in the SV and MH MOP groups, but showed no differences between the two groups. Therefore, SV MOP could be considered an effective tool for enhancing tooth movement, especially for molar distalization, uprighting, and protraction to an edentulous area.

Comparison of the effects of horizontal and vertical micro-osteoperforations on the biological response and tooth movement in rabbits / 대한치과교정학회지

Objective@#This study aimed to compare the amount of tooth movement after multiple horizontal (MH) and single vertical (SV) micro-osteoperforations (MOPs), and evaluate the histological changes after orthodontic force application in rabbits. @*Methods@#The mandibles of 24 white rabbits were subjected to two experimental interventions: MH and SV MOPs. Defect volume of the MOPs between the two groups was kept similar. A force of 100 cN was applied via a coil spring between the incisor teeth and the first premolars. The amount of tooth movement was measured. Differences in the amount of tooth movement and bone variables at three time points and between the two groups were evaluated using repeated-measures analysis of variance. @*Results@#The first premolar showed a mesial movement of 1.47 mm in the MH group and 1.84 mm in the SV group, which was significantly different at Week 3 (p < 0.05). No significant difference was observed in bone volume and bone fraction between the groups. Tartrate-resistant acidic phosphatase-positive cell count was also significantly greater at Week 3 than at Week 1 in both the SV and MH groups. @*Conclusions@#The amount of tooth movement showed significant differences between Weeks 1 and 3 in the SV and MH MOP groups, but showed no differences between the two groups. Therefore, SV MOP could be considered an effective tool for enhancing tooth movement, especially for molar distalization, uprighting, and protraction to an edentulous area.

Displacement and stress distribution of the maxillofacial complex during maxillary protraction using palatal plates: A three-dimensional finite element analysis / 대한치과교정학회지

OBJECTIVE: The purpose of this study was to analyze initial displacement and stress distribution of the maxillofacial complex during dentoskeletal maxillary protraction with various appliance designs placed on the palatal region by using three-dimensional finite element analysis. METHODS: Six models of maxillary protraction were developed: conventional facemask (Type A), facemask with dentoskeletal hybrid anchorage (Type B), facemask with a palatal plate (Type C), intraoral traction using a Class III palatal plate (Type D), facemask with a palatal plate combined with rapid maxillary expansion (RME; Type E), and Class III palatal plate intraoral traction with RME (Type F). In Types A, B, C, and D, maxillary protraction alone was performed, whereas in Types E and F, transverse expansion was performed simultaneously with maxillary protraction. RESULTS: Type C displayed the greatest amount of anterior dentoskeletal displacement in the sagittal plane. Types A and B resulted in similar amounts of anterior displacement of all the maxillofacial landmarks. Type D showed little movement, but Type E with expansion and the palatal plate displayed a larger range of movement of the maxillofacial landmarks in all directions. CONCLUSIONS: The palatal plate served as an effective skeletal anchor for use with the facemask in maxillary protraction. In contrast, the intraoral use of Class III palatal plates showed minimal skeletal and dental effects in maxillary protraction. In addition, palatal expansion with the protraction force showed minimal effect on the forward movement of the maxillary complex.

Comparison of treatment effects between four premolar extraction and total arch distalization using the modified C-palatal plate / 대한치과교정학회지

OBJECTIVE: The purpose of this study was to compare the skeletal, dental, and soft-tissue treatment effects of nonextraction therapy using the modified C-palatal plate (MCPP) to those of premolar extraction (PE) treatment in adult patients with Class II malocclusion. METHODS: Pretreatment and posttreatment lateral cephalographs of 40 adult patients with Class II malocclusion were retrospectively analyzed. The MCPP group comprised 20 patients treated with total arch distalization of the maxillary arch while the PE group comprised 20 patients treated with four PE. Fifty-eight linear and angular measurements were analyzed to assess the changes before and after treatment. Descriptive statistics, paired t-test, and multivariate analysis of variance were performed to evaluate the treatment effects within and between the two groups. RESULTS: The MCPP group presented 3.4 mm of retraction, 1.0 mm of extrusion, and 7.3° lingual inclination of the maxillary central incisor. In comparison, the PE group displayed greater amount of maxillary central incisor retraction and retroclination, mandibular incisor retraction, and upper lip retraction (5.3 mm, 14.8°, 5.1 mm, and 2.0 mm, respectively; p < 0.001 for all). In addition, the MCPP group showed 4.0 mm of distalization and 1.3 mm of intrusion with 2.9° distal tipping of the maxillary first molars. CONCLUSIONS: These findings suggest the MCPP is an effective distalization appliance in the maxillary arch. The amount of incisor retraction, however, was significantly higher in the PE group. Therefore, four PE may be recommended when greater improvement of incisor position and soft-tissue profile is required.

A follow-up study of the association between mobile phone use and symptoms of ill health

Objectives: The duration and frequency of mobile phone calls, and their relationship with various health effects, have been investigated in our previous cross-sectional study. This 2-year period follow-up study aimed to assess the changes in these variables of same subjects. Methods: The study population comprised 532 non-patient adult subjects sampled from the Korean Genome Epidemiology Study. The subjects underwent a medical examination at a hospital in 2012/2013 and revisited the same hospital in 2014/2015 to have the same examination for the characteristics of mobile phone use performed. In addition, to evaluate the effects on health, the Headache Impact Test-6 (HIT-6), Psychosocial Well-being Index-Short Form, Beck Depression Inventory, Korean-Instrumental Activities of Daily Living, Perceived Stress Scale, Pittsburgh Sleep Quality Index, and 12-item Short Form Health Survey were analyzed. For all these tests, the higher the score, the greater the effect on health. Variances between scores in all the indices in the baseline and follow-up surveys were calculated, and correlations of each index were analyzed. Results: The average duration per call and HIT-6 score of the subjects decreased significantly compared with those recorded two years ago. The results showed a slight but significant correlation between call duration changes and HIT-6 score changes for female subjects, but not for males. HIT-6 scores in the follow-up survey significantly decreased compared to those in the baseline survey, but long-time call users (subjects whose call duration was ≥5 minutes in both the baseline and follow-up surveys) had no statistically significant reduction in HIT-6 scores. Conclusions: This study suggests that increased call duration is a greater risk factor for increases in headache than any other type of adverse health effect, and that this effect can be chronic.

A follow-up study of the association between mobile phone use and symptoms of ill health

Objectives: The duration and frequency of mobile phone calls, and their relationship with various health effects, have been investigated in our previous cross-sectional study. This 2-year period follow-up study aimed to assess the changes in these variables of same subjects.Methods: The study population comprised 532 non-patient adult subjects sampled from the Korean Genome Epidemiology Study. The subjects underwent a medical examination at a hospital in 2012/2013 and revisited the same hospital in 2014/2015 to have the same examination for the characteristics of mobile phone use performed. In addition, to evaluate the effects on health, the Headache Impact Test-6 (HIT-6), Psychosocial Well-being Index-Short Form, Beck Depression Inventory, Korean-Instrumental Activities of Daily Living, Perceived Stress Scale, Pittsburgh Sleep Quality Index, and 12-item Short Form Health Survey were analyzed. For all these tests, the higher the score, the greater the effect on health. Variances between scores in all the indices in the baseline and follow-up surveys were calculated, and correlations of each index were analyzed.Results: The average duration per call and HIT-6 score of the subjects decreased significantly compared with those recorded two years ago. The results showed a slight but significant correlation between call duration changes and HIT-6 score changes for female subjects, but not for males. HIT-6 scores in the follow-up survey significantly decreased compared to those in the baseline survey, but long-time call users (subjects whose call duration was ≥5 minutes in both the baseline and follow-up surveys) had no statistically significant reduction in HIT-6 scores.Conclusions: This study suggests that increased call duration is a greater risk factor for increases in headache than any other type of adverse health effect, and that this effect can be chronic.

Familial Amyloidotic Polyneuropathy With Transthyretin Gene Mutation

Familial amyloidotic polyneuropathy (FAP) is a rare hereditary amyloidosis that is characterized by slowly progressive peripheral polyneuropathy with other systemic involvement. More than 100 amyloidogenic transthyretin gene mutations have been reported, mainly in endemic areas of Portugal, Japan, and Sweden. We describe two brothers who exhibited progressive painful sensorimotor polyneuropathy with autonomic dysfunction. Gene analysis revealed a heterozygous Asp38Ala substitution in the transthyretin gene; this represents the first reported case of FAP in Korea.

A Diagnostic Questionnaire for the Epidemiologic Studies of Childhood and Adult Atopic Dermatitis in Korea / 대한피부과학회지

BACKGROUND: Atopic dermatitis is reported to have recently increased, but it is difficult to systematically perform epidemiologic studies of atopic dermatitis. OBJECTIVE: The purpose of the present study was to create a diagnostic questionnaire for epidemiologic studies of childhood and adult atopic dermatitis in Korea. METHODS: We made up the items that were necessary for the diagnosis of atopic dermatitis in Korea on the basis of Hanifin and Rajka's guidelines and the published Korean journals. We established the diagnostic questionnaire for the epidemiologic studies of childhood and adult atopic dermatitis in Korea. RESULTS: A total of 19 questions were selected for the diagnostic questionnaire. Among them, 4 questions are related to the major diagnostic criteria for atopic dermatitis, and 15 questions are related to the minor diagnostic criteria for atopic dermatitis. CONCLUSION: We propose that this diagnostic questionnaire would be an efficient and convenient method to perform epidemiologic studies on childhood and adult atopic dermatitis in Korea.

A Case of Secondary Porphyrinopathy Induced by Chronic Alcoholism / 대한피부과학회지

The disturbance of porphyrin metabolism is principally differentiated into the porphyrias and secondary porphyrinopathies. Alcohol, drugs, heavy metal, and various diseases can cause secondary porphyrinopathy. Among them, alcohol is a major porphyrinogenic agent, and it may cause disturbances in the porphyrin metabolism, resulting in the biochemical and clinical manifestations of porphyria. We herein report on a case of secondary porphyrinopathy caused by long-term ingestion of alcohol in a 47-year-old man. He presented with painful, multiple bullae and erosion with erythematous patches on the dorsal side of both hands and arms, along with periorbital erythema and hyperpigmentation. The laboratory evaluation revealed a slight increase in urine uroproporphyrin without any abnormalities of the heme metabolites. Histopathological examination showed subepidermal bullae and vascular dilatation in the upper dermis. Periodic acid-Schiff stain revealed a mild degree of thickening of the vessel walls and the floor of the bullae. Based on these clinical, laboratory and histopathological findings, we diagnosed this case as secondary prophyrinopathy rather than porphyria.

A Case of Isolated Collagenoma / 대한피부과학회지

Collagenomas are considered to be connective tissue nevi composed predominantly of collagen. They can be hereditary or sporadic. We report herein a rare case of isolated collagenoma on the left side of the face and the left thigh without associated abnormalities, in a 30-year-old man. Histopathologically, the lesion consisted of thick collagen fibers, which was compatible with collagenoma.

A Case of Folliculosebaceous Cystic Hamartoma on the Right Nasal Ala

Folliculosebaceous cystic hamartoma is a rare cutaneous hamartoma comprised of follicular, sebaceous, and mesenchymal elements. It usually presents as an exophytic papule or nodule on the central part of the face. The histological findings are intradermal cystic structures lined by infundibular epithelium, numerous sebaceous lobules radiating from cystic structures and a surrounding stroma composed of mesenchymal changes, including variable proportions of fibrous, adipose, vascular and neural tissues. We herein report a case of folliculosebaceous cystic hamartoma in a 73-year-old man who presented with a skin-colored, dome-shaped papule on the right nasal ala.

Usefulness of distal radius by BMD using DEXA

BACKGROUND: The purpose of this study is to investigate the correlations between distal radius BMD and other skeletal sites (L2-L4, Femoral neck, Ward's triangle, Trochanter) BMDs, and to find aut the usefulness of DTX-200. METHODS: The authors surveyed the subjects of 76 perimenopausal women who had visited Kyunghee Medical Center and measured their bone mineral densities (BMDs) from February, 1997 to July, 1997. Measurements were done for distal radius, ultradistal-8mm radius BMD using DTX-200 (OSTEOMETER, Denmark), and other skeletal sites (L2-L4, Femoral neck, Wards triangle, Trochanter) BMDs using EXPERT (Lunar, USA). Using SPSS for windows, the correlation coefficients of the BMDs of both instruments were calculated. RESULTS: The total number of subjects were 76 (average age, 54.8 years, range 32~78years). Among them, 67 were postmenopausal women. The BMD measurements of various skeletal sites were as follows : distal radius, 0.41+/-0.07(g/cm2), ultradistal 8mm radius 0.34+/-0.07 (g/cm2), femoral neck 0.82+/-0.18 (g/cm2), trochanter 0.72+/-0.17 (g/cm2), Ward's triangle 0.59+/-0.22 (g/cm2), L2-L4 0.98+/-0.16(g/cm2). The correlations of BMDs between distal radius and femoral neck, trochanter, Ward's triangle, and L2-L4 were 0.44, 0.35, 0.47, and 0.63, respectively. The correlations of BMDs between ultradistal-8mm radius and femoral neck, trochanter, Ward's triangle, and L2-L4 were 0.64, 0.34, 0.41, and 0.69 respectively. CONCLUSION: The correlations of BMDs between distal radius and those of femoral neck, trochanter, Ward's triangle, L2-L4 were moderately high.

A Case of polymyalgia rheumatica

Polymyalgia rheumatica is characterized by pain and stiffness of the shoulder and pelvic girdles, morning stiffness, constitutional symptoms and an elevated erythrocyte sedimentation rate. We have experienced a 45-year-old female patient with polymyalgia rheumatica who presented with pain and stiffness of the shoulder and pelvic girdle, an elevated erythrocyte sedimentation rate and dramatic response to low-dose steroids. To our knowledge, thes is the second case of polymyalgia rheumatica with a brief review of literature.