ABSTRACT
No abstract available.
Subject(s)
Mycobacterium marinum , Mycobacterium , Polymerase Chain ReactionABSTRACT
PURPOSE: To test whether cardiac multidetector CT (MDCT) perfusion imaging can accurately delineate an irreversibly damaged myocardium in animals with an occlusive myocardial infarction. MATERIALS AND METHODS: In 16 rats, the left anterior descending coronary arteries were ligated distal to its first diagonal artery after a thoracotomy. Thirty minutes after the procedure, 16-slice MDCT (Sensation 16, Siemens, Erlangen, Germany) was performed and delayed images were obtained up to 5 minutes after injecting the contrast agent (0.2 mL/100g, 0.5 mL/sec). Ten rats were re-examined one week later. After CT scanning, the rats were sacrificed and their hearts were extirpated for 2,3,5-triphenyltetrazolium chloride (TTC) histochemical staining. The stained slices were compared with the CT images. The CT number (HU) of the infarct and non-infarct areas were estimated from the contrast ratio (CR). RESULTS: The CT attenuation in the infarct area was significantly lower than that in the normal myocardium. Quantitative analysis of the CT attenuation revealed a significant difference in the CR and CT attenuation of the infarct and reference areas (0.48+/-0.12 vs 0.64+/-0.13, p<0.05, 163+/-46 HU vs 216+/-56 HU, p<0.05). However, there were no significant differences in the CT numbers between the infarct and non-infarct areas on the one-week follow-up. CONCLUSION: A perfusion defect on MDCT indicates the myocardial damage in an animal model with occlusive myocardial infarction.
Subject(s)
Animals , Rats , Arteries , Coronary Vessels , Follow-Up Studies , Heart , Models, Animal , Myocardial Infarction , Myocardium , Perfusion Imaging , Perfusion , Thoracotomy , Tomography, X-Ray ComputedABSTRACT
We report here on a case of popliteal aneurysm and rupture that occurred over a 10-day period and this was all secondary to salmonella infection. Computed tomography (CT) angiography of the extremity that was performed before and after aneurysmal rupture showed the aneurysm's rapid evolution to rupture over a short period of time. We also review the pathogenesis, clinical presentation, diagnostic approach and management of salmonella aneurysms.
Subject(s)
Aneurysm , Angiography , Extremities , Popliteal Artery , Rupture , Salmonella Infections , SalmonellaABSTRACT
We report here on a case of popliteal aneurysm and rupture that occurred over a 10-day period and this was all secondary to salmonella infection. Computed tomography (CT) angiography of the extremity that was performed before and after aneurysmal rupture showed the aneurysm's rapid evolution to rupture over a short period of time. We also review the pathogenesis, clinical presentation, diagnostic approach and management of salmonella aneurysms.
Subject(s)
Aneurysm , Angiography , Extremities , Popliteal Artery , Rupture , Salmonella Infections , SalmonellaABSTRACT
We report the successful treatment of a postoperative pseudoaneurysm of a popliteal artery, which was associated with an arteriovenous fistula to the popliteal vein using an endovascular placement of a PTFE-covered stent graft. After a one-month follow-up, there was an in-stent stenosis, which was managed by balloon angioplasty. The patient was well with mild leg discomfort after a 3-month follow-up.