ABSTRACT
Introduction: Bronchiolitis has the major effect on patient's daily living. This study applied in order to the assessment of the quality of life in chemical warfare victims with bronchilitis obliterans
Methods: In this descriptive cross-sectional study, were selected 93 chemical warfare victims with bronchiolitis obliterans referred to respiratory clinic of Baqyatallah hospital by convenience sampling method for research. Quality of life was measured with St George's Respiratory Questionnaire
Results: Mean of scores of symptoms, activity and impact domains and global scores was 85.56, 77.38, 68.5 and 74.25 ordinary. Quality of life was significantly correlated with percent of chemical injury and reverse correlation with FEV1. Persons with diploma and up education and employees have better quality of life
Conclusion: This findings show severs decrease of quality of life in these individuals. Lower quality of life related to decrease of FEV1 and affected to eye, skin and psychology disorders show global attention to promotion of the quality of life in chemical warfare victim with bronchiolitis obliterans
ABSTRACT
To evaluate The effect of some physicochemical factors such as strain, temperature and media composition on the production of catalase Antigen. Iterventional. Four media [AMM, YED, S and CDA] which were different in kind, and amount of glucose and other ionic and aminoacid components were used at 28°c and 37°c. Also Two pathogenic human and animal isolates were used for mass Production of fungi, the mycelia were being filtered after 96 hours, were disrupted using lysing buffer, and then centrifuged at 150000g, The water soluble suppernatant, was used to purify the antigen. The amount of proteins water - Soluble were measurered by Brodford method. Then electrophorised and the sample was specificaully stained with ferocyanid. The water - sdubles were loaded on the anionic and cathionic columns, respectively. The amounts of their proteins were measured follewed by reading their O.Ds eluents of cathionic calumn were electrophorised and their electrophoretic patterns were compared. Results showed that the amount of the proteins in two S and CDA was 1/3 +/- 0/1mg/ml and in the other two YED and AMM it was 1/1 +/- 0/1mg/ml. After chromatography, still the protein amountof the first two water - soluble's [S and CDA] were more than that of the second two water - soluble's [YED and AMM]. Electrphoresis of the eluents showed that the eluents of S and CDA had stronger bands than the eluents of YED and AMM. It is concluded that strain and temperature has no effects on the protein amounts of water -solubles as well as eluents. While themedia composition had positive effect on their protein amounts. This study also showed that in contrast to the media composition, strain and tempreature has no effects on the electrophoretic Pattern of The water - solubles and eluents
ABSTRACT
Background: Chronic obstructive pulmonary disease is one of the harmful complication in chemical injuries with sulfur mustard. Corticosteroids, bronchodilators and anti cholinergic are the most common drugs use in this disease in which it isn't definitely treatment but is palliative
Materials and Methods: There were 39 patients suffered by sulfur mustard, non smoker, without history of the use of corticosteroid during last month selected based on the spirometery and American thoracic society criteria and divided into 3 group mild moderate and sever. They underwent intravenous corticosteroid for 8 days and pulmonary function test [PFT] was done before and after treatment
Results: All patients the PFT was increased after treatment FVC and FEV1 increased significantly in contrast the PEF. the results show severity of the obstructon in 33.33% patient was decreased, in 61.4% without change and in 5.12% was increased.31.65 of the patients who had mild obstruction beome better. Also 60% with moderate obstruction and 80% with sever obstruction become as same.so however the more sever obstruction, better recovery
Conclusion: This protocol is a good method to treat the moderate and sever COPD and it recommoned to not treatment the mild ones
ABSTRACT
Background: Chronic obstructive pulmonary disease is one of the harmful complication in chemical injuries with sulfur mustard. Corticosteroids, bronchodilators and anti cholinergic are the most common drugs use in this disease in which it isn't definitely treatment but is palliative
Materials and Methods: There were 39 patients suffered by sulfur mustard, non smoker, without history of the use of corticosteroid during last month selected based on the spirometery and American thoracic society criteria and divided into 3 group mild moderate and sever. They underwent intravenous corticosteroid for 8 days and pulmonary function test [PFT] was done before and after treatment
Results: All patients the PFT was increased after treatment FVC and FEV1 increased significantly in contrast the PEF. the results show severity of the obstructon in 33.33% patient was decreased, in 61.4% without change and in 5.12% was increased. 31. 65 of the patients who had mild obstruction beome better. Also 60% with moderate obstruction and 80% with sever obstruction become as same.so however the more sever obstruction, better recovery
Conclusion: This protocol is a good method to treat the moderate and sever COPD and it recommoned to not treatment the mild ones