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Journal of Biomedical Engineering ; (6): 1065-1069, 2014.
Article in Chinese | WPRIM | ID: wpr-234457

ABSTRACT

This paper proposes algorithm in predicting the RNA secondary structure that combines several sequence comparisons, searches the eigenvalue for subsequence division with dynamic programing, utilizing the minimum free energy method. Moreover, the paper assesses the results derived from this new algorithm based on base-pairs distance, climbing distance and morphology distance. The paper also compares the assessment result and the prediction results of different prediction tools, and analyzes the advantages of the new method and its improvement direction.


Subject(s)
Algorithms , Nucleic Acid Conformation , RNA , Chemistry
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