Abnormal iron metabolism after intracerebral hemorrhage / 国际脑血管病杂志

Intracerebral Hemorrhage (ICH) is a common cerebrovascular disease with high disability rate and high mortality rate.A large number of clinical and experimental studies have shown that the abnormal metabolism of iron in the brain tissue around the hematoma after ICH is an important cause of secondary brain damage such as brain edema and neuronal apoptosis.It is an important factor affecting the outcome of patients.This article reviews the abnormal metabolism of iron and its significance after ICH.

Clinical study of solitaire AB stent assisted with coil embolization therapy in the treatment of wide-necked intracranial aneurysms / 中国现代医生

Objective To explore the clinical effects of solitaire AB stent assisted with coil embolization therapy in the treatment of wide-necked intracranial aneurysms. Methods A total of 30 patients with wide-necked intracranial a-neurysms who were admitted in our hospital and given the treatment of stent combined with coil embolization technique from August 2013 to August 2014 were selected. The patients were given the treatment of anti-coagulation and anti-platelet during perioperative period. Cerebral angiography was re-examined 3 months after the surgery and embolization effect was evaluated. Results 30 patients (30 pieces) with wide-necked intracranial aneurysms were treated with soli-taire AB stent assisted with coil embolization therapy in this study, among whom 26 patients were fully and closely em-bolised, 3 patients were embolised over 90%, and 1 patient was embolised mostly (85%-90%). Follow-up was carried out for patients 2-12 months. Modified Rankin scores (mRS) was applied for evaluation. 25 patients were scored 0, 4 were scored 1 and 1 was scored 2. One of the patients died after rescue due to severe cerebral angiospasm induced by subarachnoid hemorrhage followed by diffuse brain swelling. No rupture of aneurysms was seen in other patients during the embolization surgery, and no surgery-associated complications such as stent displacement and bleeding. Satisfactory effect was achieved for patients with wide-necked intracranial aneurysms receiving stent assisted with embolization surgery. All patients were followed-up by cerebral angiography, and no relapse of arterial aneurysm was detected. Conclusion Solitaire AB stent assisted with coil embolization technique in the treatment of wide-necked intracranial a-neurysms is safe and effective.