ABSTRACT
ObjectiveTo investigate the late detection of HIV/AIDS cases in the elderly in Jilin Province and analyze its influencing factors， to provide theoretical basis for improving their life quality. MethodsThe first CD4 values of HIV/AIDS patients aged 50 years and above living in Jilin Province were used to estimate late detection， and the influencing factors of late detection in elderly cases were analyzed. ResultsThe average CD4 cell count of newly reported HIV/AIDS cases aged 50 and above in Jilin Province from 1996 to 2021 was （230.55±191.97）， the low value group accounted for the largest proportion （50.8%）， and the late detection rate was 59.3% （1397/2325）. The late detection cases were mainly from sexual transmission （46.8% for same-sex and 48.2% for heterosexual contact）. From the perspective of sample sources， most of the late detection patients were diagnosed while testing for other illnesses， followed by testing and consulting. In terms of contact history， the late detection of cases of men who have sex with men was higher. The binary logistic regression analysis showed that gender， marriage， sample source and report year were the factors affecting the late detection of AIDS. The late detection rate of males was higher， and cases of married couples were more likely to be late detection. With the increase of report year， the late detection rate decreased， and testing and counseling could effectively reduce the late detection rate of AIDS. ConclusionThe CD4 cell count in the first detection of HIV/AIDS in the elderly in Jilin Province is low， and the late detection rate of male cases is high. In recent years， the expansion of voluntary counseling and testing in Jilin Province has effectively reduced the late detection rate of HIV/AIDS. At the same time， sex education should be strengthened for the elderly， healthy marital relationships should be advocated and more attention should be paid to the mental health of the elderly.
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Objective To explore the HIV epidemic and related factors among MSM in Jilin province.Methods During the implementation of sentinel surveillance program from 2010 to 2015,continuous cross-sectional studies were conducted to monitor the awareness of AIDS,sexual behavior,HIV and syphilis positive rates,with the sample size no less than 400 in each surveillance site.Results From 2010 to 2015,a total of 7 823 MSM were involved in this study.The overall HIV prevalence among MSM was 5.4％ (42/7 823),with an increasing trend during 2010 and 2015 (Trend testx2=110.023,P＜0.001).The rates of awareness on AIDS were higher than 90.0％.The proportion of consistent condom use was 27.0％ (2 112/7 823) in the last 6 months,and significant differences were found in these years (x 2=234.038,P＜0.001).Results from multivariate logistic regression analysis showed that the HIV infection related risk factors among MSM in Jilin province would include:residency from other provinces (aOR=1.797,95％ CI:1.185-2.726),recruitment through internet (aOR=1.717,95％CI:1.332-2.215),diagnosed of having sexually transmitted diseases in the previous year (aOR=1.893,95％CI:1.356-2.643) and positive testing on syphilis (aOR=4.309,95％CI:3.097-5.995).And consistent condom uses in the last 6 months (aOR=0.387,95％CI:0.143-0.557),tested HIV in the last year (aOR=0.632,95％CI:0.375-0.891) were preventive factors.Conclusions HIV prevalence was increasing among MSM in Jilin province,but both the proportion of consistent condom use and the former HIV testing rate were at a low level.Aggressive measurement including consistent condom use and periodical HIV testing among MSM was warranted.
ABSTRACT
Objective To explore the HIV epidemic and related factors among MSM in Jilin province.Methods During the implementation of sentinel surveillance program from 2010 to 2015,continuous cross-sectional studies were conducted to monitor the awareness of AIDS,sexual behavior,HIV and syphilis positive rates,with the sample size no less than 400 in each surveillance site.Results From 2010 to 2015,a total of 7 823 MSM were involved in this study.The overall HIV prevalence among MSM was 5.4％ (42/7 823),with an increasing trend during 2010 and 2015 (Trend testx2=110.023,P＜0.001).The rates of awareness on AIDS were higher than 90.0％.The proportion of consistent condom use was 27.0％ (2 112/7 823) in the last 6 months,and significant differences were found in these years (x 2=234.038,P＜0.001).Results from multivariate logistic regression analysis showed that the HIV infection related risk factors among MSM in Jilin province would include:residency from other provinces (aOR=1.797,95％ CI:1.185-2.726),recruitment through internet (aOR=1.717,95％CI:1.332-2.215),diagnosed of having sexually transmitted diseases in the previous year (aOR=1.893,95％CI:1.356-2.643) and positive testing on syphilis (aOR=4.309,95％CI:3.097-5.995).And consistent condom uses in the last 6 months (aOR=0.387,95％CI:0.143-0.557),tested HIV in the last year (aOR=0.632,95％CI:0.375-0.891) were preventive factors.Conclusions HIV prevalence was increasing among MSM in Jilin province,but both the proportion of consistent condom use and the former HIV testing rate were at a low level.Aggressive measurement including consistent condom use and periodical HIV testing among MSM was warranted.
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Objectie:To study the protective effects and mechanism of Huoxuetongmailing(HXTML) on experimental myocardial ischemic rats by zhuodu.Methods 50 healthy male Wister rats were randomly divided into groups namely blank group,model group,Cedocard group,HXTMLmax and HXTMLmin group,10 rats in each group.Each rat had been recordⅡelectroca rdiographic(ECG) before the experiment.Hyperlipemic forage was feeded and ISO was subcutaneously injected into rats except Blank group to cause myocardial ischemia.Blank group and model group,respectively,the volume of normal saline irrigation,etc.,and the rest of the group were irrigated isosorbide dinitrate,HXTMLmax and HXTMLmin dose treatment.After treatment,the myocardium zymogram(CK,CK-MB and LDH) and inflammatory factor were detected by modern medical method.Results:HXTMLmax and HXTMLmin dose could signifi cantly reduce the levels of serum enzymes(P