ABSTRACT
Viable protoscolices of Echinococcus granulosus injected into Swiss-albino mice by two different routes, viz. intraperitoneal and subcutaneous and in two different concentrations of 2000 and 1000 scolices, to observe the development of cysts have shown that subcutaneous route of infecting a mouse model is superior because of its low infecting dose and longer survival period of mouse. This finding should be helpful in experiments to observe the effect of drugs for the treatment of hydatidosis, in vivo, without the need of killing the mouse.
Subject(s)
Animals , Disease Models, Animal , Echinococcosis/parasitology , Echinococcus granulosus/pathogenicity , Humans , Injections, Intraperitoneal , Injections, Subcutaneous , Mice , Survival Analysis , Time FactorsABSTRACT
Staphylococcus aureus has shown a disconcerting propensity to develop resistance to antimicrobial agents and an increasing proportion of these have become resistant to methicillin as well. Regular surveillance should be carried out in every hospital and stringent infection control measures and vigorous treatment should be employed to prevent the nosocomial spread of MRSA. A total of 1056 MRSA were isolated from various specimens received in bacteriology division of SKIMS Srinagar out of which 46.32% were from inpatients and 31.87% from outpatients. None of these strains showed resistance to vancomycin and a good proportion were sensitive to amikacin (80.75%) gentamicin (69%) or ciprofloxacin (63.25%).