Motor nerve conduction velocity and biphenyl hydantoin serum level-a study in epileptic patients

Motor nerve Conduction velocity was determined in the ulnar nerve and lateral popliteal nerve for epileptic patients receiving DPH. The results were correlated with the serum DPH levels as determined spectrophotometrically. No positive correlation was demonstrated statistically between both parameters. It is suggested that the lowering of conduction, velocity that might take place in some patients receiving DPH is most probably an idiosyncrasic effect of the drug