ABSTRACT
Background: Urinary tract infection is a collective term for infections that involve any part of the urinary tract. It is one of the most common infections in local primary care. There are wide range of factors identified that can increase susceptibility to UTI, like sexual intercourse, congenital abnormalities, urinary obstruction, prior history of UTI, diabetes, urogenital surgery, estrogen deficiency. Diabetes mellitus has been a significant risk factor for complicated UTI. Presence of microalbumin in urine in patients of urinary tract infection may be a predictor of intrinsic renal pathology and its presence is a predictor of ongoing progressive damage to kidneys. Microalbuminuria is also associated with cardiovascular events and diabetic nephropathy. Early diagnosis of microalbuminuria will decrease the incidence of end stage renal disease and cardiovascular events. The present study was thus conducted to evaluate prevalence of microalbuminuria in patients diagnosed with urinary tract infections.Material & Methods:The present hospital based case control study was conducted on 60 patients visiting the outpatient clinic (OPD) of Department of Urology, Government Medical College and Rajindra Hospital, Patiala and diagnosed with UTI and the control group consisted of 20 age and gender matched individuals. Estimation of urine microalbumin was done by Enyme linked immunoassay(ELISA) kit method in Department of Biochemistry, GMC Patiala.Results:Out of 60 cases of UTI included in the present study, prevalence of microalbuminuria was observed in 43.3% among cases of UTI . A total of 85% of the cases with positive urine culture had microalbuminuria (p<0.01).Conclusions:Microalbuminuria and ACR can be recommended for predicting ESRD at an early stage of kidney disease.
ABSTRACT
Background: Severe Acute Respiratory Syndrome Corona Virus 2(SARS?CoV?2) is the novel corona virus first detected in Wuhan in 2019. nCOV belongs to the ?-corona virus cluster. As the third most highly pathogenic corona virus, the clinical presentations of 2019-nCoV infection resemble those of the other two corona viruses, Severe Acute Respiratory Syndrome Corona Virus (SARS-CoV) and Middle East Respiratory Syndrome Corona Virus (MERS-CoV). The abnormalities in the laboratory indices particularly the Blood Biochemical parameters may be associated with the severity of multiple organ dysfunction seen in COVID-19. The aim of the present project was to analyze the laboratory diagnostic profile of sars?cov?2 (covid?19) patients & to study the associated factors.Methods: The present hospital � based cross sectional study was conducted on all the patients who had tested positive for COVID & were admitted in Rajindra Hospital, Patiala in the time period of the July 2020 to December 2020, during the declared Corona Virus Pandemic. All the Biochemical Parameters were estimated on the automatic Analysers.Results: The results of the present study show abnormalities in the Renal Function Tests, Liver Function Tests, Blood sugar levels and Serum Electrolytes. Blood sugar levels and Renal function tests are significantly deranged in the patients of Covid 19 having co-morbidities like Diabetes Mellitus, Hypertension, CAD, CKD, Hypothyroidism etc: Conclusions:Biochemical Laboratory parameters
ABSTRACT
Background: Onset of first menstrual cycle also termed as “menarche” signifies the initiation of sexual maturation of girls. The present study aims to represent an amalgam of menstrual awareness, perceptions and hygiene in light of the associated menstrual practices prevalent in the adolescence girls of Nahan.Methods: A cross-sectional data of 189 girls aged between 10 to 16 years were collected from Nahan, district Sirmaur in Himachal Pradesh. Data regarding perceptions, awareness and hygienic conditions during menstruation were also gathered through an interview based schedule.Results: Menarche was known to be a normal physiological process by only 53.43% girls, while the rest of the participants didn’t know the reason for its occurrence. For 81.2% girls the informant was their mother and a very little role was played by sisters (5.36%), books (0.67%), friends (6.04%) and relatives (5.36%). Most of the girls (95.28%) used sanitary napkin as absorbent for menstrual flow, but the use of single sanitary napkin for 7 to 8 hours by 48% participants was of alarming concern. Stomachache was the most common problem associated with menarche, whereas breast heaviness (16.98%), body ache (16.03%) and backache (26.41%) were witnessed in considerable proportion of girls. A significant number of girls (78.3%) were prohibited from entering in the holy places/temples during this period.Conclusions: Although menarcheal health is acquiring greater significance across the globe, but the age old social restrictive practices associated with menstruation are still common and prevalent in this societies.
ABSTRACT
Background: The objective of the current study was to study the effects of preoperative use of topical anti-inflammatory prednisolone acetate, nepafenac and placebo, on the sustenance of intraoperative mydriasis during cataract surgery. Methods: This study comprised of 60 patients scheduled for cataract surgery. Patients (20 in each group) were randomized to receive placebo, prednisolone acetate, and nepafenac. These eye drops were given 3 times daily for the 2 days prior to surgery. The pupillary diameters were measured by the surgeon using Casterveijo’s Caliper before the corneal section and at the end of surgery. The primary result was the number of patients with pupil ≥6 mm at the end of the surgery; the secondary result was the number of patients with pupil ≥6 mm at the beginning of the surgery. It was a single-center, masked, randomized clinical study. Results: All the patients achieved pupil ≥6 mm at the beginning of the surgery. The number of patients in the prednisolone (16/20) and nepafenac (17/20) groups with pupil ≥6 mm was greater than in the placebo group in the maintenance of intraoperative mydriasis (7/20 – p=0.003). There was no statistically significant difference among the prednisolone and nepafenac groups in the maintenance of intraoperative mydriasis (p=0.791). There were no complications during surgery or related to the pre-operative use of the eye drops. Conclusion: Pre-operative use of prednisolone acetate and nepafenac was effective in maintaining the intraoperative mydriasis when compared with placebo.