ABSTRACT
Background: Nanoparticle coated implants have revolutionized the field of implantology. Peri-implantitis is one of the main for implant failure. Most implant failures are due to Streptococcus mutans, Staphylococcus aureus, Porphyromonas gingivalis, and Actinomyces concomitant. Aim: To evaluate and compare the antibacterial effect of titanium, zirconium, aluminum nanoparticles against S. aureus and P. gingivalis at 24, 72 hrs and 1 week intervals. Materials and Methods: According to ISO/TR 11175:1993, the samples were prepared in disc shape with 20-mm diameter and 1-mm thickness in Grade IV titanium. The samples were decontaminated by sonicating in acetone and subsequently in water three times for 15 min. A total of eighty samples were made, then coated with nanoparticles, and divided into Group-A (control), Group-B (Ti nanoparticles coating), Group-C (Zi nanoparticles coating), and Group-D (Al nanoparticles coating). The discs were sterilized under ultraviolet radiation and placed in Mueller-Hinton agar medium for S. aureus and blood agar for P. gingivalis. The colonies were counted at 24, 72 hrs and 1 week intervals. Statistical Analysis Used: The values were statistically analyzed using one-way ANOVA and Tukey honestly significant difference test. Results: The P < 0.001 showed that statistically significant difference in colony forming unit had been found in titanium nanoparticles coated samples at 24, 72 hrs and 1 week intervals. Conclusion: TiO2 nanoparticle coated titanium discs showed significant antibacterial effect.
ABSTRACT
Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis. Purpose: To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag° in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins. Materials and Methods: Ag° were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h. Results: Group D showed multifold decrease in the colony-forming units. Conclusion: The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.