ABSTRACT
Diarrhea is a frequent complication in patients with cancer. It may be caused by several factors including conventional gastrointestinal pathogens, suppression of normal intestinal flora as well as noninfectious causes such as mucositis and bowel ischemia, with neutropenic enterocolitis [NE] being the most serious. To study diarrhea in neutropenic cancer patients in the pediatric age group, with its underlying etiologies and risk factors especially the bacterial causes with special concern on NE. The study was carried out at the Pediatric Hematology and Oncology Units, Zagazig University Hospitals, Egypt, from Januray 2009 to September 2010. Neutropenic cancer patients who developed diarrhea were grouped into 2 groups: group [1], with NE, and group [2], with neutropenic diarrhea rather than NE, On the first day of diarrhea, patients were subjected to: complete blood count, blood cultures [if febrile], stool microscopy [for red and white blood cells, ova and parasites], and stool culture [for specific pathogens]. Abdominal ultrasonography was carriad out within 3 days of the onset of diarrhea. A total of 200 children