ABSTRACT
To explore one-step method for the preparation of Ganoderma lucidum multicomponent microemulsion, according to the dissolution characteristics of triterpenes and polysaccharides in Ganoderma lucidum, formulation of the microemulsion was optimized. The optimal blank microemulsion was used as a solvent to sonicate the Ganoderma lucidum powder to prepare the multicomponent microemulsion, besides, its physicochemical properties were compared with the microemulsion made by conventional method. The results showed that the multicomponent microemulsion was characterized as (43.32 +/- 6.82) nm in size, 0.173 +/- 0.025 in polydispersity index (PDI) and -(3.98 +/- 0.82) mV in zeta potential. The contents of Ganoderma lucidum triterpenes and polysaccharides were (5.95 +/- 0.32) and (7.58 +/- 0.44) mg x mL(-1), respectively. Sonicating Ganoderma lucidum powder by blank microemulsion could prepare the multicomponent microemulsion. Compared with the conventional method, this method is simple and low cost, which is suitable for industrial production.
Subject(s)
Emulsions , Fungal Polysaccharides , Materia Medica , Chemistry , Medicine, Chinese Traditional , Particle Size , Powders , Reishi , Chemistry , Solubility , Technology, Pharmaceutical , Methods , TriterpenesABSTRACT
In order to comprehensively understand current situation about studies on channels and to open train of thought for the study, the relative literatures are analyzed and summarized from morphology, biophysics, biochemistry and so on. Probe into existing models of channel lines from nerves, blood vessels and nerves, gap junction, connective tissue; summarize biophysical characte-ristics of channels from temperature, loose connective tissue, biopressure effect, coherence electromagnetic field, etc.; and summarize biochemical characteristics of channels from ion concentration, exhalant of CO2, extracellular matrix and enzymology on the channel lines. Although the studies have not revealed essence of channel lines, these results reflect survey of studies on tissue structures and biological characteristics of channel lines at present.