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J. Vasc. Bras. (Online) ; J. vasc. bras;19: e20200054, 2020. graf
Article in Portuguese | LILACS | ID: biblio-1135081

ABSTRACT

Resumo As úlceras de perna são as complicações cutâneas mais comuns em pacientes com anemia falciforme. Acometem principalmente indivíduos homozigotos e são lesões de difícil cicatrização e recidivantes, com impactos físicos, psicológicos e econômicos. Neste trabalho, discutimos a apresentação clínica, o diagnóstico, a fisiopatologia das úlceras falcêmicas e as suas implicações sobre a terapêutica.


Abstract Leg ulcers are the most common cutaneous complication of sickle cell disease. These lesions occur mainly in homozygous forms, are slow to heal and often relapse, causing negative physical, emotional, and economic impacts. In this paper, we discuss the clinical presentation, diagnosis, and pathophysiology of sickle cell leg ulcers and their implications for treatment.


Subject(s)
Humans , Anemia, Sickle Cell/complications , Leg Ulcer/etiology , Wound Healing , Leg Ulcer/diagnosis , Leg Ulcer/physiopathology , Leg Ulcer/therapy
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