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Objective:To investigate the effect of milking diary combined with syringe collection of colostrum on early lactation.Methods:Totally 80 cases of separated mothers and infants hospitalized in the maternity ward of our hospital from February to November 2018 were selected as research objects, February to June as control group, July to November as experimental group, 40 cases respectively, two groups were given routine maternal lactation, experimental group in regular maternal lactation guidance, on the basis of guiding diary records milking and provides the syringe collection of colostrum. Comparison of two groups of maternal postpartum 3 days milking frequency and milking, lactation, start time, lactation Ⅱ period time, breast tenderness and 42 days exclusive breastfeeding rates.Results:Postpartum 24 hours, 48 hours, 72 hours of milking times of delivery woman in experimental group were respectively (7.25 ± 1.53), (7.40±1.26), (8.50±0.82) times, which were higher than (4.18 ± 2.62), (6.35±1.73), (7.35±1.72) times in control group, the difference was statistically significant ( t values were -6.408, -3.102, -3.824, P < 0.01). Milking 49-72 hours was 50.30 ml, which was significantly higher than 30.70 ml of control group, the difference was statistically significant ( Z value was 3.773, P < 0.01); mammary start time, lactation Ⅱ period significantly ahead of time, respectively (9.82 ± 3.62) hours in advance, and (15.83 ±0.78) hours, the difference was statistically significant ( t values were 2.480,4.871, P<0.05); breast pain Ⅲ degrees within 72 hours of experimental group 5.0% (2/40) was significantly lower than the control group 25.0% (10/40), 42 days exclusive breastfeeding rate 62.5% (25/40) was significantly higher than the control group 22.5% (9/40), the differences were statistically significant ( χ2=6.772, 13.095, P<0.05). Conclusion:Joint syringe collection colostrum milk a diary method can effectively improve maternal milk, increase the amount of milk secretion, and early lactation start time and duration of lactation Ⅱ period, so as to promote exclusive breastfeeding rate and duration of breastfeeding, and can effectively reduce the degree of breast tenderness, worthy of clinical popularization and application
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Objective@#To study the epidemiologic and genetic characteristics of coxackievirus A6(CV-A6) strains isolated in Shenyang.@*Methods@#Enterovirus strains positive for neither enterovirus A71 (EV-A71) nor CV-A16 were isolated from Shenyang during 2013 to 2017 to screen for CV-A6 isolates by real-time PCR. The entire sequences of viral genes encoding VP1 of CV-A6 positive samples were amplified and sequenced. The phylogenetic analysis was performed.@*Results@#CV-A6 strains accounted for 27.83% (575/2 066) of the non-EV-A71 and non-CV-A16 enterovirus strains isolated in Shenyang during the years 2013 to 2017. And CV-A6 strains were the predominant enterovirus strains with positive rate of 68.38 % (240/351) in 2015. The CV-A6 isolates from Shenyang during 2013 to 2017 could be classified into the cluster D3a in the phylogenetic tree. Subtype D3a.1 strains circulated during 2013 to 2014 and subtype D3a.2 strains circulated during 2015 to 2017.@*Conclusions@#CV-A6 strains were the predominant enterovirus strains among non-EV-A71 and non-CV-A16 enterovirus strains circulated in Shenyang from 2013 to 2017. The CV-A6 isolates from Shenyang during 2013 to 2017 could be classified into the cluster D3a in the phylogenetic tree and subtype D3a.2 strains were evolved from subtype D3a.1 strains.
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Objective To explore the incidence of early complications within 72 hours among patients with six kinds of acute organophosphorus pesticide poisoning,thus to provide reference for the clinical treatment.Methods The retrospective study analyzed the clinical data of 335 cases with acute oral organophosphorus pesticide poisoning treated in Emergency Department of 307 Hospital of PLA from July 2008 to December 2015.Patients were divided into six groups according to the results of serum toxicology tests:acute phorate group (group A),acute dichlorvos group (group B),acute omethoate group (group C),acute dimethoate group (group D),acute phoxim group (group E) and acute parathion group (group F).The incidence of complications among the six groups were compared.The main analysis method was ranks test.Results There were no significant differences among the six groups in the incidence of cerebral edema,liver injury,kidney injury,myocardial injury,gastrointestinal hemorrhage and acute pancreatitis (P ＞ 0.05),while the mortality and the incidence of sudden cardiac arrest (SCA),respiratory failure,circulatory failure,multiple organ dysfunction syndrome (MODS),coagulation disorders and capillary leak syndrome (CLS) were significantly different among the six groups (P ＜ 0.05).The incidence of SCA wihin 24 hours in acutedichlorvos group reached up to 17.8％,and in other groups was as follows:acute parathion group (11.1％),acute dimethoate group (8.9％),acute phorate group (7.8％) and acute omethoategroup (1.5％).However,no one developed SCA in acute phoxim group.The total incidence of circulatory failure in all patients was 10.1％;dichlorvos group 31.1％ and dimethoate group (22.2％) had higher rates than other groups.The incidence of respiratory failure in all groups reached over 20％,while the total incidence was 36.7％,whereby,acute phorate group with a high of 46.7％,acute dichlorvos group with 44.4％,acute parathion group with 44.4％ and acute dimethoate group with 42.2％,respectively.The total incidence of coagulation disorders was 9.6％,while the incidences of the acute dichlorvos group (24.4％),acute phorate group (11.6％) and acute parathion group (11.1％) were higher than 10％.CLS confined to occur in acute dichlorvos group (11.1％) and acute phorate group (2.5％).However,MODS occurred mainly in acute dichlorvos group (28.9％) and acute parathion group (22.2％).Conclusions The incidences of early complications among the six groups are different,while acute oral dichlorvos poisoning patients tend to occur SCA.Within 72 h of poisoning,acute phorate poisoning group is more prone to respiratory failure,and acute dichlorvos poisoning group is more likely to develop coagulopathy disorders,circulation failure,CLS and MODS.Those patients in acute omethoate and acute phoxim poisoning groups have less risk to develop life-threatening complications except respiratory failure.