ABSTRACT
Abstract: Acute generalized exanthematous pustulosis (AGEP) is an acute febrile rash, usually induced by drugs, which recently has been linked to spider bite. We report a case of a male patient, 48 years old, with an erythematous rash accompanied by fever and small non-follicular pustules. He reported previous pain in the buttock with the onset of a necrotic plaque. The lesion was compatible with spider bite of the genus Loxosceles. According to the EuroSCAR group instrument, the patient scored +10 indicating definite diagnosis of AGEP. As the patient had a compatible lesion and had no other triggers of AGEP, in an Loxosceles endemic area, the AGEP would be associated with spider bite, as described in other publications.
Subject(s)
Humans , Animals , Male , Middle Aged , Spider Bites/complications , Acute Generalized Exanthematous Pustulosis/etiology , Acute Generalized Exanthematous Pustulosis/pathology , Skin/pathology , Buttocks , Erythema/etiology , Erythema/pathology , Exanthema/etiology , Exanthema/pathology , Brown Recluse SpiderABSTRACT
Abstract A case of exuberant pretibial mucinosis in a patient with normal thyroid function is reported. A review of literature on possible etiologies other than thyroid disease for the accumulation of mucin in the pretibial area is presented. In the patient described, it is possible that vascular insufficiency is involved. However, this is not the only factor responsible for the accumulation of mucin, since there are still unidentified causes and many patients with vascular diseases do not develop similar injuries.
Subject(s)
Aged , Female , Humans , Mucinoses/etiology , Mucinoses/pathology , Dermis/pathology , Erythema/etiology , Erythema/pathology , Mucins/analysis , Tibia , Vascular Diseases/complicationsABSTRACT
A Síndrome de Sweet é uma doença cutânea rara, caracterizada por lesões eritêmatoedematosas, febre e neutrofilia. Aproximadamente 20% dos casos são relacionados a neoplasias, sendo raros os casos associados à neoplasia de endométrio relatados na literatura.Relata-se o caso de uma paciente feminina, 64 anos, portadora de adenocarcinoma de endométrio, que evoluiu com aparecimento de Síndrome de Sweet na sua forma paraneoplásica, com resolução espontânea das lesões
Sweet's syndrome is a rare skin disease characterized by erythematous, edematous lesions, fever and neutrophilia. Approximately 20% of cases are related to neoplasms, with rare cases associated with endometrial cancer reported in the literature. Here the authors report the case of a 64-year-old female patient with endometrial adenocarcinoma, which progressed with the appearance of Sweet's syndrome in its paraneoplastic form, with spontaneous resolution of the lesions