ABSTRACT
In surgical management of esophageal carcinoma bilateral trunkal vagotomy is unavoidable and this has some effect on the intrathoracic stomach. So, the purpose of this study was to assess the function of the intrathoracic stomach after vagotomy. This work was conducted on 23 patients with esophageal carcinoma and 10 healthy persons as a control group. Fasting serum gastrin [FSG] was estimated by radioimmunoassay and residual free acidity [RFA] was measured by HCl titration. There was preoperative normoacidity among esophageal carcinoma patients who showed marked reduction in the early postoperative period. Three months later they showed fair acid secretion. Preoperative FSG level was within normal range, one month later there was hypergastrinemia which returned back to normal values 3 months postoperatively. So, it was concluded that intrathoracic stomach has been showed to restore its acid secretory level as well as its gastrin secretion level 3 months after esophagogastrectomy
Subject(s)
Humans , Male , Female , Esophagectomy/methodsABSTRACT
Fasting levels of blood lipids were studied in 41 patients with schistosomal hepatic fibrosis and 81 controls. The effect of gatroesophageal decongestion operation [Hassab's operation] on two groups of S.H.F. patients: group A of 18 patients with evident collaterals and group B of 14 patients without, were investigated. The means of fasting total lipids [TL], cholesterol [CH], cholesterol esters [CE], percent esterification of cholesterol, triglycerides [TG], phospholipids [PL] and alpha lipoproteins were found to be significantly lowered in the S.H.F. patients than controls. This was much more marked in group A. Hassab's operation was followed by a significant increase in TL, CH, CE and PL in group A, and not in group B. TG, alpha lipoprotein per cent and percent esterification of cholesterol were not affected in both groups. The possible mechanisms responsible for the above data are discussed