[Chemical composition and antibacterial activity of the essential oil of salvia macrochlamys boiss. and kotschy, from West Azarbayjan Province]

In the Flora Iranica this genus is represented by fifthy-eight species, seventheen of which are endemic. The genus Salvia are known for medicinal value, antibacterial and antioxidant properties. Investigation on essential oil of Salvia macrochlamys and antibacterial activity assessment. The aerial parts of S. macrochlamys were collected during the flowering stage from Marmishuo Hill in West-Azarbayjan Province, in July 2006 and were hydrodistilled for 3 hours, using a Clevenger-type apparatus to yield 0.35% [w/w] of yellowish oil and analyzed with GC and GC/MS. The constituents of the essential oil were identified by comparison of their mass spectra and retention indices [RI] with those given in the literature and authentic samples. Antibacterial activities of the essential oil were investigated according to the disc diffusion method and MIC value. Thirty-four compounds were characterized in the essential oil of S. macrochlamys, representing 97.6% of the oil, of which beta-Caryophyllene [32.7%], 1, 8-Cineol [18.9%], were found to be the major components. The oil of S. macrochlamys showed high antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Staphylococcus epidermidis. The oil of S. macrochlamys consists of monoterpen [44.4%] and sequiterpens [52.0%]. The antibacterial avtivity can be attributed to 1, 8-Cineol

[Chemical composition and antibacterial activity of the essential oil of salvia hydrangea from two localities of Iran]

The genus Salvia L. [Lamiaceae] consists of 58 annual and perennial species in Iran, of which 17 are endemic. S. hydrangea DC. ex Benth. with common Persian name of "Gol-e Arooneh" has been used in folk medicine of Iran as antiinflammatory, antispasmodic, carminative and sedative. Infusion of flowers was used for treating cold in traditional medicine of Fars province. Study of chemical composition and antibacterial activity of the essential oils of S. hydrangea from two different localities of Iran. Aerial parts of S. hydrangea were collected in full flowering stage from two different localities; Abadeh [Fars province] and Takab [Azarbaijan province]. The oils were obtained by hydrodistillation using a Clevenger type apparatus and analyzed by GC and GC-MS instruments. Antibacterial activities of the oils were evaluated by disc diffusion method. MIC values were measured by microdilution broth susceptibility assay. The essential oils yield of Abadeh and Takab were 0.1 and 0.13% [w/w] based on dry weight of plants, respectively. Thirty-seven and 35 compounds were identified in the oil samples which constituted 97.4 and 98.3% of the total oils, respectively. In the oil obtained from Abadeh, beta-caryophyllene [25.2%], 1,8-cineole [15.2%] and caryophyllene oxide [11.1%] were found as the major components. From Takab sample beta-caryophyllene [26.2%], 1, 8-cineole [14.2%] and alpha-pinene [11.2%] were characterized as the main compounds. The oils showed moderate antibacterial activity. The differences observed in essential oil composition of two studied samples could be attributed to their different ecological, geographical and edaphical origin factors. The moderate antibacterial activity of the oils could be associated with the presence of 1, 8-cineole