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Arq. bras. endocrinol. metab ; 52(2): 334-339, mar. 2008.
Article in Portuguese | LILACS | ID: lil-481002

ABSTRACT

Com a intensificação do controle glicêmico no tratamento do diabetes melito tipo 1 (DM1), houve uma mudança progressiva das causas de mortalidade com destaque para a DCV. A identificação de fatores de risco, como a dislipidemia, tornou-se de grande importância para minimizar o risco de complicações crônicas micro e macrovasculares. As diretrizes para prevenção de doença coronariana em diabetes, geralmente, fazem referência ao diabetes melito tipo 2 (DM2), com pouca recomendação específica para o DM1. Definir alvos terapêuticos ou indicação de intervenção farmacológica é mais controverso nesse tipo de diabetes, em virtude da faixa etária desses pacientes. O presente estudo busca destacar a importância de estabelecer o diagnósti-co da dislipidemia nesse grupo de pacientes e instituir terapêutica adequa- da e precoce, objetivando alcançar as metas estabelecidas para reduzir o perfil lipídico aterogênico desses pacientes.


With the intensive glycemic control in the therapy of type 1 diabetes mellitus (T1DM) patients, cardiovascular disease has been the main cause of mortality. Identification of risk factors, such as dyslipidemia is considered of great importance in terms of avoiding chronic micro and macro vascular complications. The statements for prevention of coronary artery disease in diabetes are generally are related do type 2 diabetes mellitus and little attention is paid to T1DM. Defining therapeutical targets and indications for treatment are more controversial in these patients due to their young ages. The present study aims to emphasize the importance of establishing the diagnosis of dyslipidemia in this group of patients as well as indicate the appropriate and early treatment, in order to reach the targets of treatment and reduce the atherogenic lipid profile.


Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Young Adult , Diabetes Mellitus, Type 1/drug therapy , Diabetic Angiopathies/drug therapy , Dyslipidemias/drug therapy , Hypolipidemic Agents/therapeutic use , Blood Glucose/analysis , Cholesterol, HDL/analysis , Cholesterol, LDL/analysis , Diabetes Mellitus, Type 1/complications , Diabetic Angiopathies/etiology , Diabetic Angiopathies/prevention & control , Dyslipidemias/diagnosis , Dyslipidemias/etiology , Monitoring, Physiologic , Risk Factors , Treatment Outcome , Young Adult
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