ABSTRACT
Background- COVID-19 is the Pandemic disease caused by the SARS-COV-2 virus. There are many myths regarding COVID-19 vaccine spread by community people at rural area. The objective of this study was to assess the knowledge about myths of COVID-19, Bhopal Ratua (M.P). The World Health Organization (WHO) is working closely with global experts, governments, and partners to rapidly expand scientific knowledge on this new virus, to track the spread and virulence of the virus, and to provide advice to countries and individuals on measures to protect health and prevent the spread. The urban people have poor attitude regarding myths about Covid- 19 vaccination. Materials & Methods- A Study was conducted to assess the knowledge and attitude regarding Covid Vaccination among rural community people. 30 rural community people from a selected rural community were included in the study. A questionnaire consisting of 40 questions was used. Results- Almost all had some pre-test knowledge regarding the myths surrounding Covid-19. Whereas the knowledge was increased post-test. Conclusion- We concluded that such awareness programs may have a positive impact on increasing the knowledge of rural people. After that the vaccine needs to go through a review by the National Regulatory Authority, who will decide if the vaccine is safe and effective.
ABSTRACT
Respiratory syncytial virus (RSV) is the single most important viral agent causing pediatric lower respiratory tract infections (LRTIs) worldwide. To evaluate the role of RSV in pediatric LRTIs, we studied 85 children <2 years of age hospitalized for community-acquired LRTIs. Nasopharyngeal aspirates were obtained on admission for the detection of RSV antigen by immunochromatographic assay. Demographic, clinical, and radiological findings for RSV antigen were compared. Data analysis was performed by Chi-square test. A relatively higher number of RSV-infected children 32 (60.4%) were below 6 months of age. Clinical and radiological findings in both RSV-positive and RSV-negative groups were comparable. RSV antigen was positive in 53 (62.4%) with immunochromatography. Our study confirms that RSV plays a significant role in community-acquired LRTIs in children.
ABSTRACT
Co-infection due to Mycobacterium tuberculosis, Cryptococcus and Naegleria fowleri has not been reported till now in literature, to the best of our knowledge. Here we report a curious case of co-infection of the central nervous system due to these three pathogens in an apparently immune-competent, HIV negative boy. The 15 year old boy was a diagnosed case of tubercular meningitis and was on anti-tubercular and anti-epileptic treatment. However, two months later he presented again in the emergency department with sudden loss of consciousness. His CSF showed presence of capsulated budding yeast cells (suggestive of Cryptococcus) and flagellated parasites (resembling the flagellated stage of Naegleria fowleri). CSF was also positive for Cryptococcal antigens by Latex Agglutination test. The boy was HIV negative and apparently immuno-competent. He was subsequently put on amphotericin B therapy for six weeks. Repeat microscopy, done towards the end of amphotericin B course, showed clearing of CSF. However, the patient’s condition improved only slightly, owing to neurological damage caused by the pathogens as suggested by brain CT and MRI scans. Thus infection caused by the members of three different kingdoms in an apparently immunocompetent boy highlights the importance of thinking beyond the ordinary causative pathogens, and actively searching for rarer etiologies to ensure timely intervention; especially in nonresponsive cases.