ABSTRACT
Polycystic ovary syndrome Polycystic Ovarian Syndrome is a disease characterized by unovulation and formation of immature follicles result in menstrual irregularities, hyperandrogenemia, hirsutism and infertility. This study was aimed to show the changes in oxidative status in these women, in accordance to changes in serum antioxidant vitamins A,C,E. Thirty Polycystic Ovarian Syndrome women included in this study, their serum FSH, LH, Prolactin and testosterone hormones were measured .also serum concentrations of vitamin A, C, E were determined. These women are divided into three groups according to their hormonal changes. Group [1] involves women with high level of prolactin. Group [2] involves women with LH/FSH ratio more than one. Group [3] involves women with LH/FSH ratio less than one. All groups are compared with 10 apparently healthy fertile women. All groups show significant decrease in serum concentrations of vitamins in compare with control women .This indicates different hormonal changes increase oxidative stress in Polycystic Ovarian Syndrome women by different mechanisms. Polycystic Ovarian Syndrome produce significant reductions in serum antioxidant vitamins A, C and E when compared with control