ABSTRACT
Infectious complications following heart transplantation are an important cause of morbidity and mortality. Generally, bacterial infections are predominant; however, fungal infections can be responsible for up to 25 percent of infectious events. We report the case of a patient who presented with histoplasmosis as an infectious complication five years after heart transplantation due to a chagasic cardiopathy. This association has rarely been reported in the international literature
Subject(s)
Humans , Male , Adult , Chagas Cardiomyopathy/surgery , Heart Transplantation/adverse effects , Histoplasmosis/diagnosis , Histoplasmosis/etiologyABSTRACT
Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the majority of cases, muscular weakness has been interpreted as polymyositis. We report the case of a 48-year-old woman suffering from classic PBC, in association with a myopathy whose histological features are distinct from the cases reported before. We also performed a MEDLINE research for PBC and concomitant muscular diseases
Subject(s)
Humans , Female , Middle Aged , Liver Cirrhosis, Biliary/complications , Polymyositis/etiology , Liver Cirrhosis, Biliary/diagnosis , Liver Cirrhosis, Biliary/pathology , Polymyositis/pathologyABSTRACT
Neste trabalho de atualizaçäo, os autores apresentam os critérios diagnósticos para infarto agudo do miocárdio, bem como traçam condutas terapêuticas, priorizando o atendimento nas seis primeiras horas de instalaçäo da doença. A ênfase é dada para a utilizaçäo dos trombolíticos, que embora sejam drogas empregadas em muitos estudos, em várias partes do mundo, ainda apresentam diversas controvérsias; tais como: o tipo de trombolítico, a via de administraçäo, os critérios de inclusäo e exclusäo dos pacientes e os protocolos utilizados, dentre outros.