ABSTRACT
Background: Malaria is an important infectious vector borne disease caused by a Plasmodium species. Liver involvement in severe Plasmodium falciparum infection is commonly a significant cause of morbidity and mortality among humans. Objective: In this study, we show the correlation of malaria positive cases with liver derangement. Methods: The present study had been conducted in Teerthankar Mahaveer Medical college Hospital and Research Center, Moradabad, U.P. from February 2014 to January 2015 on both IPD & OPD patients .Results: The present study included 200 clinically suspected cases of Malaria with derange Liver function. 67.5% patients show increased level of Total and indirect bilirubin followed by 45% of patient shows increased level of direct bilirubin. 27.5% patient’s shows increased level SGPT followed by 40% of SGOT. Conclusions: Deranged liver functions are commonly seen as a complication of severe malarial infection.
ABSTRACT
Introduction: The worldwide escalation in both community- and hospital-acquired antimicrobial-resistant bacteria is threatening the ability to effectively treat patients, emphasizing the need for continued surveillance, more appropriate antimicrobial prescription, prudent infection control, and new treatment alternatives. Objective: To study the prevalence of bacteria from the different samples (Blood, Urine, CSF, PUS) and to examine the antibiotic sensitivity pattern of isolated organisms. Methods: Around n=150 samples of Urine, Blood, CSF and Pus sample were collected from the patient attending Teerthanker Mahaveer medical Hospital college and Research Centre. Results: Out of 150 clinical samples, highest number of isolates were gram-positive, Staphylococcus aureus n=47 (31.33%) followed by E. Coli n=37(24.66%), Klebseilla n=33(22.00%), Pseudomonas n=11(07.33%). S. aureus was highly sensitive to Gentamycin (88.09%) and least sensitive to Co-trimoxazole (14.28%). Tobramycin & Linezolid were 95.23% sensitive followed by Amikacin (90.47%), Meropenem (90.47%), Levofloxacin (88.09%). Conclusion: In our study Staphylococcus aureus to be most common isolates followed by Escherichia coli, Klebseilla, Pseudomonas, Citrobacter, Proteus.